Tumor pathologies of the prostate gland are represented by benign prostate tumor and prostate cancer and are generally seen after 50 years. The objective of this work was to study the epidemiological, clinical, paraclinical and therapeutic aspects of prostate tumors at the General Reference Hospital of Panzi (DRC). Patients and Methods: Retrospective cross-sectional study on 70 patients followed in hospital or on an outpatient basis for prostate tumor in the urology department of the General Reference Hospital of Panzi from January 1, 2013 to December 31, 2017. The epidemiological, clinical and paraclinical parameters (pathology with Gleason score, prostate volume on ultrasound, urinary impact on ultrasound, urea level, creatinine level and PSA level) and therapeutics were studied. Results: Prostate tumors represent 3.84% of surgical pathologies. The average age of the patients was 68.2 years with the extremes of 47 and 90 years old. The patients were transferred in 78.6% of the cases. Acute urine retention was the most common reason for consultation with 42.8%. The PSA rate > 4 ηg in 92.9% of the cases. Benign prostatic hyperplasia was found in 62.8% of patients against 35.7% of prostate adenocarcinoma and 41.7% of prostate cancers were moderately differentiated. The prostate volume was 41 -60 g in 35.7% of the cases. No urinary impact in 71.4% of patients. Surgical treatment was in 85.7% and RTUP was the most used at 40%. A hospital stay between 15 and 21 days in 30% of cases. The cure rate was 81.4% and 14.3% developed urethral stenosis. Conclusion: Prostate tumors are common in people over the age of 50 who see for acute retention of urine. Benign enlarged prostate is the most common.