Candida-Associated Denture Stomatitis in Patients After Immunosuppression Therapy

Golecka, M.; Ołdakowska‐Jedynak, Urszula; Mierzwińska-Nastalska, Elżbieta; Adamczyk-Sosińska, E.

doi:10.1016/j.transproceed.2005.12.078

Cited by 48 publications

(49 citation statements)

References 5 publications

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“…The repeated treatments with antibiotics and sulphonamides can be predisposing factors because of the microbial alterartions that they provoke in the oral cavity (9). Xerostomy Qualitative and quantitative alterations of the salivary flow in elderly patients is probably secondary to the assumption of drugs, above all the antihypertensive ones, rather than a primary functional deficit.…”

Section: Kidneys Affectionsmentioning

confidence: 99%

Candida-associated denture stomatitis

Salerno

Pascale²,

Contaldo³

et al. 2011

Med Oral

288

231

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Candida albicans is a dimorphic yeast strongly gram positive able to live as normal commensal organism in the oral cavity of healthy people. It is the yeast more frequently isolated in the oral cavity. Under local and systemic factors related to the host conditions, it becomes virulent and responsible of oral diseases known as oral candidiasis. It has been shown that the presence of denture is a predisposing factor to the onset of pathologies related to C. albicans. Clinical studies have shown that C. albicans is not only able to adhere to the mucous surfaces, but also to stick to the acrylic resins of the dental prostheses. Both the plaque accumulated on the denture and the poor oral hygiene contribute to the virulence of Candida, offering the clinical picture of Candida-associated denture stomatitis. The therapeutic strategies currently adopted in the clinical practice to overcome these fungal infections provide for the use of topical and/or systemic antifungal and topical antiseptics and disinfectants, the irradiation with microwaves and the accurate mechanical removal of the bacterial plaque from the denture surfaces and from the underlying mucosa. A correct oral hygiene is important for the control of the bacterial biofilm present on the denture and on the oral mucosa and it is the fundamental base for the prophylaxis and the therapy of the Candidaassociated denture stomatitis.

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Section: Kidneys Affectionsmentioning

confidence: 99%

Candida-associated denture stomatitis

Salerno

Pascale²,

Contaldo³

et al. 2011

Med Oral

288

231

View full text Add to dashboard Cite

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“…1,2 This phenomenon, in association with factors such as trauma, diet, poor hygiene or predisposing systemic conditions (xerostomia, hormonal alterations and immunodepression caused by diabetes mellitus or HIV infection), may lead complete denture users to develop a condition known as denture stomatitis. [3][4][5][6][7] This condition is clinically characterized by a discrete focal inflammation on the palatum, which can evolve to an intense erythema in all area covered by the denture and, in some cases, to papillary hyperplasia. 6 According to Daniluk et al 5 (2006), Candida genus yeasts can be isolated from the human oral cavity in 64.9% of patients with denture stomatitis, being Candida albicans the most prevalent species (78.4%).…”

Section: Introductionmentioning

confidence: 99%

“…[3][4][5][6][7] This condition is clinically characterized by a discrete focal inflammation on the palatum, which can evolve to an intense erythema in all area covered by the denture and, in some cases, to papillary hyperplasia. 6 According to Daniluk et al 5 (2006), Candida genus yeasts can be isolated from the human oral cavity in 64.9% of patients with denture stomatitis, being Candida albicans the most prevalent species (78.4%). In fact, studies have shown that regardless of the presence of clinical symptoms, Candida albicans is more prevalent in complete denture users than in the general population.…”

Section: Introductionmentioning

confidence: 99%

Effect of sodium bicarbonate on Candida albicans adherence to thermally activated acrylic resin

et al. 2009

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The purpose of this study was to evaluate the effect of 5% sodium bicarbonate on the adherence of Candida albicans to thermally activated acrylic resin. Fifty 4 mm² specimens of acrylic resin were obtained using a metallic matrix. The specimens received chemical polishing, were sterilized and then immersed in Sabouraud broth, inoculated with Candida albicans standardized suspension. After 24 hours of incubation at 37°C, the specimens were divided into four groups according to the substance used for disinfection (5% sodium bicarbonate, 0.12% digluconate chlorhexidine, vinegar and Corega Tabs). A control group was included, in which distilled water was used. The adhered microorganisms were dispersed, diluted and plated onto culture media to determine the number of colony-forming units (cfu/mL). The results were analyzed through the Mann-Whitney statistical test at the 5% level of significance. Only 0.12% digluconate chlorhexidine and 5% sodium bicarbonate presented a statistically significant difference (p = 0.0010 and p = 0.0156, respectively) compared to the control group, decreasing the number of cfu/mL. However, when the different disinfecting solutions were compared with each other, only 0.12% digluconate chlorhexidine presented a statistically significant difference in the reduction of cfu/mL. It was concluded that although 0.12% digluconate chlorhexidine was more effective in the reduction of Candida albicans adherence values to thermally activated acrylic resin, 5% sodium bicarbonate also proved to be a viable alternative.

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“…A candidíase oral, quando acomete pacientes portadores de próteses dentárias, é descrita como estomati te protéti ca e tem sido considerada a lesão bucal mais freqüentemente observada em usuários de próteses removíveis, apresentando uma prevalência de 60 a 72% 1,2 . Clinicamente, esta lesão caracterizase pela presença de múlti plos pontos hiperêmicos na região palati na sob as próteses removíveis, e em casos mais avançados, também podem ser observadas áreas eritematosas difusas, ou ainda, hiperplasia papilar do palato 1,3 .…”

Section: Metodologiaunclassified

Avaliação Clínica e Microbiológica do Tratamento da Estomatite Protética com Tintura de Schinus terebinthifolius Raddi (Aroeira)

Soares¹,

Oliveira²,

Paulo³

et al. 2010

Pesq Bras Odontoped Clin Integr

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Objeti vo: Avaliar a efi cácia clínica da ti ntura da aroeira no tratamento da estomati te protéti ca. Método: Foram selecionados 18 pacientes usuários de próteses removíveis com diagnósti co clínico para estomati te protéti ca ti po II e presença de candidose associada à prótese, constatados a parti r de um exame clínico e micológico. Os pacientes foram distribuídos em dois grupos: GT (grupo teste) -tratamento com a ti ntura da aroeira; GC (grupo controle), tratamento com nistati na. Todos os pacientes foram orientados a higienizar a prótese com escova e denti frício e, em seguida, aplicar o produto na mucosa palati na e na superfí cie da prótese 3 vezes ao dia, durante 15 dias consecuti vos, remover a prótese à noite e armazená-la em um recipiente com água. No 15º dia de uso, foi realizado um novo exame clínico e micológico para avaliar a efi cácia do tratamento. Os dados foram analisados com os testes Wilcoxon e Mann-Whitney com nível de signfi cância de 5%. Resultados: Observou-se eliminação do processo infl amatório e da infecção por Candida spp. em 66,7% e 77,8% dos casos, respecti vamente, para GT. Já para GC, a eliminação do processo infl amatório e da infecção fúngica ocorreu em 77,8% e 88,9% dos casos, respecti vamente. Estes resultados foram estati sti camente signifi cantes (Wilcoxon p=0,01). Não foi observada diferença estatí sti camente signifi cante entre os dois tratamentos (Mann-Whitney p>0,05). A infecção fúngica foi diagnosti cada apenas na prótese em todos os casos, sendo a C. albicans o microorganismo mais prevalente, estando presente em 94,4% dos casos. Conclusão: O tratamento com a ti ntura da aroeira foi efi caz no tratamento da estomati te protéti ca, promovendo remissão do processo infl amatório e da infecção por Candida spp. Avaliação Clínica e Microbiológica do Tratamento da Estomatite Protética com Tintura de Schinus terebinthifolius Raddi (Aroeira) RESUMO DESCRITORES ABSTRACTEstomati te sob prótese; Ensaio clínico; Candida.Stomati ti s, denture; Clinical trial; Candida. KEYWORDS Objecti ve:To evaluate the clinical effi cacy of Schinus terebinthifolius Raddi (aroeira) ti ncture in the treatment of denture stomati ti s. Method: Eighteen removable denture wearers with clinical diagnosis of type II denture stomati ti s and presence of candidosis associated to the denture use, as confi rmed by clinical and mycological examinati ons, were selected for the study. The pati ents were allocated to two groups: TG (test group) -treatment with Schinus terebinthifolius Raddi (aroeira) ti ncture; CG (control group), treatment with nystati n. All pati ents were instructed to clean the dentures with toothbrush and denti frice, and then apply the product on the palatal mucosa and on denture surface 3 ti mes a day, during 15 consecuti ve days, removing the denture at bedti me and keeping it in a receptacle with water. At the 15th day of use, the clinical and mycological examinati ons were redone to evaluate treatment effi cacy. Data were analyzed stati sti cally by Wilcoxon and Mann-Whitney tests at ...

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Candida-Associated Denture Stomatitis in Patients After Immunosuppression Therapy

Cited by 48 publications

References 5 publications

Candida-associated denture stomatitis

Candida-associated denture stomatitis

Effect of sodium bicarbonate on Candida albicans adherence to thermally activated acrylic resin

Avaliação Clínica e Microbiológica do Tratamento da Estomatite Protética com Tintura de Schinus terebinthifolius Raddi (Aroeira)

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