Candida brain abscess: a sonographic mimicker of intracranial hemorrhage

Intraventricular fungus ball: a unique manifestation of refractory intracranial candidiasis in an immunocompetent neonate

“…1,5,8,9 Intracranial candidiasis has also been reported to cause secondary complications, including basilar arterial thrombosis; 4 however, we found no reports of candidal fungus balls in our search of the literature. As such, there is no evidence-based approach for the treatment of intraventricular fungus balls.…”

“…[1][2][3][5][6][7][8][9] Intracranial candidal infections in immunocompetent patients have been reported in the English literature, 8 but intracranial candidiasis is typically seen in immunocompromised patients or premature infants with systemic infections. Intracranial candidiasis is seen in 2.6-12.9% of premature infants and as many as 20% of those of extremely low birth weight.…”

Sequelae associated with cerebral candidiasis in two premature infants

“…Some authors have reported on premature infants with large parenchymal abscesses in the brain noted at autopsy which appeared as areas of abnormal echogenicity on ultrasound (6)(7)(8). Some authors have reported on premature infants with large parenchymal abscesses in the brain noted at autopsy which appeared as areas of abnormal echogenicity on ultrasound (6)(7)(8).…”

“…Risk factors include prolonged exposure to antibiotic therapy, hyperalimentation/ intravenous fat emulsion, intravascular catheters and endotracheal intubation (1)(2)(3)(4). Although there have been several reports of candidal meningitis, with incidences ranging from 27 to 64% of systemic candidiasis cases, only a few reported cases of candidiasis involving the brain parenchyma were found in a recent search of the literature (1)(2)(3)(4)(5)(6)(7)(8)(9)(10)(11)(12). In each of these cases, the infant died, precluding long-term follow-up.…”

Multiple brain abscesses in a premature infant: complication of Staphylococcus aureus sepsis

“…Furthermore, CSF cultures have a reportedly low yield of bacteriologic isolation, being positive in less than 10% of cases (13,15,16). A wide range of organisms have been indicated as causing brain abscesses (17). The most frequently noted bacteria are Streptococcus and Staphylococcus.…”