Candida laryngotracheitis: a complication of combined steroid and antibiotic usage in croup

Membranous laryngitis in a child

“…Additionally, there was no evidence of membranous plaques within the trachea or subglottis which would be suggestive of bacterial tracheitis nor did the membranes on the glottis and supraglottis bleed easily when removed as happens with Diphtheria. The candida colonization was most likely due to prolonged steroid use described previously [15].…”

State of the Evidence for Standard-of-Care Treatments for Croup: Are We Where We Need to Be?

“…In a more recent trial in which 28 children received nebulized dexamethasone, 2 children with neutropenia developed bacterial tracheitis. 21 Burton et al 22 reported the occurrence of Candida laryngotracheitis as a complication of steroid and antibiotic treatment in a child with croup.…”

Adult Herpetic Laryngitis With Concurrent Candidal Infection

“…Immunosuppression associated with oral steroid use has been reported to be a potential risk factor for Candida species overgrowth in the larynx and trachea. 12 The patient described herein was a longtime smoker with COPD who had been treated with 48 mg of methylprednisolone daily, a dosage that was tapered to 8 mg/d for 2 weeks before the episode of laryngitis occurred. Additionally, the patient used an inhaled corticosteroid (fluticasone propionate [Floven]) as needed.…”