“…The study characteristics of the 28 articles included, all were candidate gene studies published between 2008 and 2017, are shown in Table 1 . Most were cohort studies (Wang et al, 2008 ; Filipski et al, 2009 ; Goekkurt et al, 2009 ; Chen et al, 2010 ; Khrunin et al, 2010a , 2012 , 2014 ; KimCurran et al, 2011 ; Tzvetkov et al, 2011 ; Erculj et al, 2012 ; Iwata et al, 2012 ; Windsor et al, 2012 ; Xu et al, 2012 , 2013 ; Zhang and Zhou, 2012 ; Zhang et al, 2012 ; Hinai et al, 2013 ; Khokhrin et al, 2013 ; Lamba et al, 2014 ; Yuan et al, 2015 ; Hattinger et al, 2016 ; Powrozek et al, 2016 ; Chang et al, 2017 ) and none were genome wide association studies (GWAS). Key details of subject characteristics [e.g., ethnicity and inclusion criteria (Sprowl et al, 2012 )], type of chemotherapy regimens (Erculj et al, 2012 ; Sprowl et al, 2012 ; Powrozek et al, 2016 ), and nephrotoxicity criteria (Goekkurt et al, 2009 ; Kim et al, 2012 ; Khrunin et al, 2014 ) were not reported in some studies.…”