Candiduria in Hospital Patients: A Study Prospective

Kobayashi, Cláudia Castelo Branco Artiaga; Fernandes, Orionalda de Fátima Lisboa; Miranda, Karla Carvalho; Sousa, Efigênia Dantas de; Silva, Maria do Rosário Rodrigues

doi:10.1023/b:myco.0000038436.51918.d9

Cited by 91 publications

(72 citation statements)

References 13 publications

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“…This study showed that in most cases of candiduria the patient had a urinary catheter (92.6%). Similar results have been obtained by Kobayashi et al (2004), who verified that 84.4% of the patients with candiduria had a catheter. According to Klotz and Smith (1990), yeasts are able to adhere to the catheter, allowing colonization in this device.…”

Section: Discussionsupporting

confidence: 88%

Candida colonization in intensive care unit patients' urine

Passos

Sales

Maciel

et al. 2005

Mem. Inst. Oswaldo Cruz

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Section: Discussionsupporting

confidence: 88%

Candida colonization in intensive care unit patients' urine

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Sales

Maciel

et al. 2005

Mem. Inst. Oswaldo Cruz

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“…These data are in accordance with other Brazilian studies [42][43][44][45] . In our study the frequency of UTI/1,000 urinary catheter (UC) days was greater than in studies realized in developing countries 46 , and although these infections are responsible for almost 40% of all NI, they continue to be unrepresentative in Brazilian hospitals, considering that the majority of them (80%) are associated with the use of urinary catheters 47,48 .…”

supporting

confidence: 93%

Nosocomial infections in a pediatric intensive care unit of a developing country: NHSN surveillance

Porto

Mantese

Arantes

et al. 2012

Rev. Soc. Bras. Med. Trop.

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Introduction: This study aimed to determine the epidemiology of the three most common nosocomial infections (NI), namely, sepsis, pneumonia, and urinary tract infection (UTI), in a pediatric intensive care unit (PICU) in a developing country and to define the risk factors associated with NI. Methods: We performed a prospective study on the incidence of NI in a single PICU, between August 2009 and August 2010. Active surveillance by National Healthcare Safety Network (NHSN) was conducted in the unit and in a case control approach, children with NI (cases) were compared with a matched controls without NI. Results: We analyzed 172 patients; 22.1% had NI, 71.1% of whom acquired it in the unit. The incidence densities of sepsis, pneumonia, and UTI per 1,000 patients/day were 17.9, 11.4, and 4.3, respectively. The most common agents in sepsis were Enterococcus faecalis and Escherichia coli (18% each); Staphylococcus epidermidis was isolated in 13% of cases. In pneumonias Staphylococcus aureus was the most common cause (3.2%), and in UTI the most frequent agents were yeasts (33.3%). The presence of NI was associated with a long period of hospitalization, use of invasive devices (central venous catheter, nasogastric tube), and use of antibiotics. The last two were independent factors for NI. Conclusions: The incidence of NI acquired in this unit was high and was associated with extrinsic factors. Keywords: Nosocomial infections. Pediatric ICU. Surveillance system. RESUMO Introdução:O objetivo deste estudo foi determinar a epidemiologia das três infecções hospitalares (IH) mais comuns -sepse, pneumonia e infecção do trato urinário (ITU) -em uma unidade de terapia intensiva pediátrica (UTIP) de um país em desenvolvimento e definir os fatores de risco associados com IH. Métodos: Nós desenvolvemos um estudo prospectivo de incidência de IH em uma única UTIP, entre agosto/2009 e agosto/2010. Foi conduzida uma vigilância ativa pelo National Healthcare Safety Network (NHSN) na Unidade e as crianças com IH (casos) foram comparadas com um grupo (controles) em um estudo caso-controle. Resultados: Nós analisamos 172 pacientes, 22,1% com IH, 71,1% adquirida na Unidade. A densidade de incidência de sepse, pneumonia e ITU por 1.000 pacientes/dia foram 17,9, 11,4, e 4,3, respectivamente. Os agentes mais comuns na sepse foram Enterococcus faecalis e Escherichia coli (18% cada), e Staphylococcus epidermidis foram isolados em 13% dos casos. Nas pneumonias Staphylococcus aureus foram os agentes mais comuns (3,2%), e nas ITUs os agentes mais frequentes foram os fungos (33,3%). A presença de IH foi associada com tempo de hospitalização prolongado, uso de procedimentos invasivos (CVC, sonda nasogástrica) e uso de antibióticos. Os dois últimos foram fatores independentes para o desenvolvimento de IH. Conclusões: A incidência de IH adquirida na Unidade foi alta, associada a fatores de risco extrínsecos. Palavras-chaves: Infecções hospitalares. UTI pediátrica. Sistema de vigilância.Nosocomial infection (NI) constitutes a major health pro...

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“…The principal risk factors include antibiotic therapy, urinary catheterization, surgical procedures, female sex and extended hospitalization. 3 Moreover, multiple site colonization with Candida species is also being commonly recognized as a major risk factor for invasive fungal infections in critically ill patients. 4 There is paucity of data from India on fungal infections in the critical care setting with variable results.…”

Section: Original Articlementioning

confidence: 99%

Epidemiology of fungal infections in critical care setting of a tertiary care teaching hospital in North India: a prospective surveillance study

Singh¹,

Kashyap²,

Ahluwalia³

et al. 2014

JCSR

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Background: During recent years, fungal infections have risen exponentially and are a cause of significant morbidity and mortality in hospitalized patients, especially in the critical care setting. There is paucity of data from India on fungal pathogens. Methods:We prospectively studied patients admitted to medical and surgical critical care section of a tertiary care institute in northern India. The clinical samples of patients were processed in Department of Microbiology for isolation and identification of fungi by using standard protocols over a period of one year. The patients were categorized into fungal infection and colonization groups. The demographic data and risk factors for fungal infection and colonization were evaluated.Results: Ninety one (82.7%) of the 110 patients enrolled in the study, had fungal infection, whereas 19 (17.3%) had fungal colonization. Candida were isolated from 85/91 (93.4%) and 19/19 (100%) patients with fungal infection and colonization respectively. There was predominance of non-albicans Candida spp both in fungal infection 61/85 (71.7%) patients as well as fungal colonization group 16/19 (84.2% ). In non-albicans Candida spp., Candida tropicalis was the most common isolate observed in both fungal infection (85.3%) and fungal colonization (63.1%) groups. Overall, in patients with fungal infection, candiduria was detected in 68/91 (74.7%) whereas candidaemia was observed in 19/ 91 (20.8%) patients. The risk factors for fungal infections included urinary catheterization (85.7%), central line insertion (81.3%), mechanical ventilation (52.7%), use of corticosteroids (23.1%), total parentral nutrition (6.6%) and peritoneal dialysis (3.3%). Conclusions:The emergence of non-albicans Candida similar to the trends in the western countries should be a cause of concern in our country. Proper surveillance of fungal pathogens is important to improve quality of care in critical care setting and measures should be focussed to control these infections, especially in patients with these risk factors.

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Candiduria in Hospital Patients: A Study Prospective

Cited by 91 publications

References 13 publications

Candida colonization in intensive care unit patients' urine

Candida colonization in intensive care unit patients' urine

Nosocomial infections in a pediatric intensive care unit of a developing country: NHSN surveillance

Epidemiology of fungal infections in critical care setting of a tertiary care teaching hospital in North India: a prospective surveillance study

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