Cannabis derivatives therapy for a seronegative stiff-person syndrome: a case report

Vicente-Valor, M.I.; Garcia-Llopis, Paula; Andujar, Ludivine; Cámara, G. Antonino de la; Busto, Natalia García del; Tinoco, M.J. López; Vergara, B Quintana; Vilaplana, Cristina; Moran, Jeff; Alcaraz, Ana

doi:10.1111/j.1365-2710.2012.01365.x

Cited by 10 publications

(7 citation statements)

References 6 publications

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“…The response to 75 Kosseifi et al 76 Schmidt et al 77 Thumen et al 78 Chamard et al 79 Lemieux et al 80 Byrne et al 81 Krishna et al 82 Aghajanzadeh et al 83 Badzek et al 84 Derksen et al 38 Rakcevic et al 85 Kelly et al 86 Kobayashi et al 87 Koca et al 88 Laroumagne et al Hegyi. 40 Iwata et al 34 Prasad 89 Sanefuji et al 90 Schreiber et al 41 Lorenzoni et al 33 Clardy et al 14 Newton et al 42 Vicente-Valor et al 43 Sharma et al 91 Pakeerappa et al 92 Ueno et al 35 Tremor and Other Hyperkinetic Movements http://www.tremorjournal.org…”

Section: Discussionmentioning

confidence: 99%

“…The majority of cryptogenic cases in this review reported symptomatic improvement. However, some of the success was with novel interventions for SPS (including spinal cord stimulation, 32 physical therapy, 40 dantrolene, 41 intrathecal baclofen, 42 and cannabis 43 ). We find this likely constitutes a reporting bias, since it is possible that cases in which novel interventions were unsuccessful may not have been published.…”

Section: Discussionmentioning

confidence: 99%

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Clinical Spectrum of Stiff Person Syndrome: A Review of Recent Reports

Sarva

Deik

Ullah

et al. 2016

Tremor and Other Hyperkinetic Movements

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Background: ''Classic'' stiff person syndrome (SPS) features stiffness, anti-glutamic acid decarboxylase (anti-GAD) antibodies, and other findings. Anti-GAD antibodies are also detected in some neurological syndromes (such as ataxia) in which stiffness is inconsistently present. Patients with otherwise ''classic'' SPS may either lack anti-GAD antibodies or be seropositive for others. Hence, SPS cases appear to fall within a clinical spectrum that includes conditions such as progressive encephalomyelitis with rigidity and myoclonus (PERM), which exhibits brainstem and autonomic features. We have compiled herein SPS-spectrum cases reported since 2010, and have segregated them on the basis of likely disease mechanism (autoimmune, paraneoplastic, or cryptogenic) for analysis. Methods: The phrases ''stiff person syndrome'', ''PERM'', ''anti-GAD antibody syndrome'', and ''glycine receptor antibody neurological disorders'' were searched for in PubMed in January 2015. The results were narrowed to 72 citations after excluding non-English and duplicate reports. Clinical descriptions, laboratory data, management, and outcomes were categorized, tabulated, and analyzed. Results: Sixty-nine autoimmune, 19 paraneoplastic, and 13 cryptogenic SPS-spectrum cases were identified. SPS was the predominant diagnosis among the groups. Roughly two-thirds of autoimmune and paraneoplastic cases were female. Anti-GAD antibodies were most frequently identified, followed by antiamphiphysin among paraneoplastic cases and by anti-glycine receptor antibodies among autoimmune cases. Benzodiazepines were the most commonly used medications. Prognosis seemed best for cryptogenic cases; malignancy worsened that of paraneoplastic cases. Discussion: Grouping SPS-spectrum cases by pathophysiology provided insights into work-up, treatment, and prognosis. Ample phenotypic and serologic variations are present within the categories. Ruling out malignancy and autoimmunity is appropriate for suspected SPS-spectrum cases.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Clinical Spectrum of Stiff Person Syndrome: A Review of Recent Reports

Sarva

Deik

Ullah

et al. 2016

Tremor and Other Hyperkinetic Movements

View full text Add to dashboard Cite

show abstract

Section: Discussionmentioning

confidence: 99%

Clinical Spectrum of Stiff Person Syndrome: A Review of Recent Reports

Sarva

Deik

Ullah

et al. 2016

Tremor and Other Hyperkinetic Movements

View full text Add to dashboard Cite

“…[ 77 ] Various studies reported that the neurological manifestations of the paraneoplastic syndrome could be relieved by conducting a plasmapheresis process. [ 78 79 ]…”

Section: Breast Cancer Metastases To the Neurocraniummentioning

confidence: 99%

A review of the neurological complications of breast cancer

Hajhamidiasl

Moradi

Movahednia

et al. 2022

Journal of Family Medicine and Primary Care

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Conducting broad assessments of the main burden of breast cancer is the core factor for improving overdiagnosis and overtreatment of breast cancer patients as well as their survival rates. Breast cancer patients may experience neurological complications that cause devastating effects on them. Chemotherapy-induced peripheral neuropathy (CIPN) and neuropathic pain are two of the most reported complications. Objective: This study aims to review the neurological complications of breast cancer and the ways to control and treat them. Comprehensive searches were carried out about the keywords of Breast Cancer, Neurological Complications, and Breast Cancer Consequences. These keywords were searched through the most well-known databases of MEDLINE, PUBMED, Cochrane Library, Best Evidence, CancerLit, HealthSTAR, and LegalTrac. In this regard, 83 articles were chosen to be included in this study from 2010 to 2021. The identification and treatment process of neurologic syndromes are not easy. The main neurologic syndromes which the breast cancer patients face are opsoclonus myoclonus syndrome (OMS), encephalitis, sensorimotor neuropathy, retinopathy, cerebellar degeneration, and stiff-person’s syndrome. CIPN and neuropathic pain are among the most prevalent side effects which are categorized as neurological complications and mainly seen 1 year after the management of breast cancer. Aiming to minimize the burden following the treatment of breast cancer, these complications should be diagnosed and treated accurately.

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Cannabis derivatives therapy for a seronegative stiff-person syndrome: a case report

Cited by 10 publications

References 6 publications

Clinical Spectrum of Stiff Person Syndrome: A Review of Recent Reports

Clinical Spectrum of Stiff Person Syndrome: A Review of Recent Reports

Clinical Spectrum of Stiff Person Syndrome: A Review of Recent Reports

A review of the neurological complications of breast cancer

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