Cannabis sativa L. in the cosmeceutical industry: prospects and biotechnological approaches for metabolite improvement

de Andrade, Camila Moreno Lopes; Caetano, Thais Teixeira Valério; Campos, Francisco Kimerling; Gandra, Vinicius Martins; Alves, Fernando Henrique Ferrari; Stein, Vanessa Cristina

doi:10.1016/j.sajb.2023.08.008

Cited by 1 publication

(1 citation statement)

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“…Although CBD oil-containing products are sold in many health food stores and drugstores in the form of food supplements, toothpastes, mouth sprays, and drops, their effect on the oral cavity has not been investigated yet [201]. Cannabis-based lotions, creams, ointments, oils, and salves are produced by the cosmetic industry [202]. Since we have previously mentioned the anti-microbial properties of cannabis [26][27][28], it seems plausible that its extracts and phytochemicals may be used as cosmetic preservatives.…”

Section: Alternative Medicinementioning

confidence: 99%

Cannabis as a Source of Approved Drugs: A New Look at an Old Problem

Gabarin,

Yarmolinsky,

Budovsky

et al. 2023

Molecules

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Cannabis plants have been used in medicine since ancient times. They are well known for their anti-diabetic, anti-inflammatory, neuroprotective, anti-cancer, anti-oxidative, anti-microbial, anti-viral, and anti-fungal activities. A growing body of evidence indicates that targeting the endocannabinoid system and various other receptors with cannabinoid compounds holds great promise for addressing multiple medical conditions. There are two distinct avenues in the development of cannabinoid-based drugs. The first involves creating treatments directly based on the components of the cannabis plant. The second involves a singular molecule strategy, in which specific phytocannabinoids or newly discovered cannabinoids with therapeutic promise are pinpointed and synthesized for future pharmaceutical development and validation. Although the therapeutic potential of cannabis is enormous, few cannabis-related approved drugs exist, and this avenue warrants further investigation. With this in mind, we review here the medicinal properties of cannabis, its phytochemicals, approved drugs of natural and synthetic origin, pitfalls on the way to the widespread clinical use of cannabis, and additional applications of cannabis-related products.

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