Cap-shaped gold nanoparticles for an optical biosensor

Himmelhaus, Michael; Takei, Hiroyuki

doi:10.1016/s0925-4005(99)00393-7

Cited by 187 publications

(158 citation statements)

References 18 publications

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“…The aggregation of nanoparticles or the formation of multilayers was not observed. Our results were in agreement with the well-known properties that provided a suitable platform for LSPR-based substrates as reported previously [37,38].…”

Section: Characterization Of the Gold-capped Nanoparticle Substratesupporting

confidence: 93%

A localized surface plasmon resonance based immunosensor for the detection of casein in milk

Hiep

Endo

Kerman

et al. 2007

Science and Technology of Advanced Materials

141

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In this research, a localized surface plasmon resonance (LSPR) immunosensor based on gold-capped nanoparticle substrate for detecting casein, one of the most potent allergens in milk, was developed. The fabrication of the gold-capped nanoparticle substrate involved a surface-modified silica nanoparticle layer (core) on the slide glass substrate between bottom and top gold layers (shell). The absorbance peak of the gold-capped nanoparticle substrate was observed at $520 nm. In addition, the atomic force microscopy (AFM) images demonstrated that the nanoparticles formed a monolayer on the slide glass. After immobilizing anti-casein antibody on the surface, our device, casein immunosensor, could be applied easily for the detection of casein in the raw milk sample without a difficult pretreatment. Under the optimum conditions, the detection limit of the casein immunosensor was determined as 10 ng/mL. Our device brings several advantages to the existing LSPR-based biosensors with its easy fabrication, simple handling, low-cost, and high sensitivity. r

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Section: Characterization Of the Gold-capped Nanoparticle Substratesupporting

confidence: 93%

A localized surface plasmon resonance based immunosensor for the detection of casein in milk

Hiep

Endo

Kerman

et al. 2007

Science and Technology of Advanced Materials

141

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“…Nanosphere lithography [94,95] or natural lithography [96] is a VPD-based surface modification technique where colloids or nanospheres are used as lithographic masks for creating patterns on surfaces. The presence of an external shadow mask between the source and the substrate creates a deposition pattern on the substrate in traditional VPD techniques.…”

Section: Nanosphere Lithographymentioning

confidence: 99%

Fabrication, Assembly, and Application of Patchy Particles

Pawar

Kretzschmar

2010

Macromol. Rapid Commun.

450

411

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The site‐specific engineering of colloidal surfaces has provided a powerful approach to pushing the boundaries of today's materials research. The resulting surface‐anisotropic and patchy particles have become the center of vital research areas, ranging from the need for large‐scale fabrication techniques to exploring new applications of these materials. This Review summarizes patchy particle fabrication techniques, including but not limited to particle and nanosphere lithography and glancing‐angle deposition. The variety of existing patchy particle fabrication techniques is revealed and the need for a scalable approach to high‐volume patchy particle production is identified. Ongoing modeling efforts describing patchy particle interactions and properties are reviewed as potential predictive tools. Research endeavors that deal with the directed assembly of patchy particles in electric and magnetic fields, as well as with supraparticular assembly through chemical interactions, are discussed. The Review is concluded with a note on the future application of patchy particles as phoretic motors.magnified image

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“…In particular, Janus particles, with two sides of distinct compositions or textures, have many potential uses: electronic paper, where one needs to switch between black and white states [4]; optical, chemical or biological biosensors, where the two hemispheres will respond differently to stimuli [5]; anisotropic building blocks for supra-assemblies, allowing a greater variety of novel structures to be built [6]; functional surfactants, where each hemisphere likes or dislikes some other component [7]; or self-motile colloidal particles (swimmers), propelled by the different ways in which either hemisphere interacts with the surrounding medium [8].…”

Section: Spheresmentioning

confidence: 99%

Soft Janus, wrinkles and all

et al. 2016

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Right now you are probably sitting on a comfy cushion. This is most likely filled with polyurethane (PU) foam. PUs are very long molecules made up of many repeating units. If the repeating units are prepolymers -intermediate-mass building blocks -with more than two reactive end groups, a three-dimensional network will form -a rubber, or elastomer, which can behave elastically depending on the degree of network cross-linking.

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Cap-shaped gold nanoparticles for an optical biosensor

Cited by 187 publications

References 18 publications

A localized surface plasmon resonance based immunosensor for the detection of casein in milk

A localized surface plasmon resonance based immunosensor for the detection of casein in milk

Fabrication, Assembly, and Application of Patchy Particles

Soft Janus, wrinkles and all

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