Capabilities, limitations, and misconceptions of using OCT to assess vulnerable plaques

Brezinski, Mark E.

doi:10.1038/nrcardio.2014.62-c1

Cited by 6 publications

(2 citation statements)

References 9 publications

(13 reference statements)

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“…Second, the authors also stated axial core lengths were statistically longer in the highest-risk groups (rACS and sAMI) compared with ls-SAP, although the relevance of this was not addressed. Acknowledging the limitations of using registry data and current OCT characterization criteria, the data provide a compelling argument that a failed plaque-healing response may be a crucial factor in plaque-rupture progression to ACS.…”

mentioning

confidence: 67%

Comparing the Risk Factors of Plaque Rupture and Failed Plaque Healing in Acute Coronary Syndrome

Brezinski

2019

JAMA Cardiol

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confidence: 67%

Comparing the Risk Factors of Plaque Rupture and Failed Plaque Healing in Acute Coronary Syndrome

Brezinski

2019

JAMA Cardiol

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“…Ultrasound cannot identify if a tumor is cancerous or not, as sound waves are highly attenuated by multiple layers of the human body. Te OCT employs light waves rather than sound waves like ultrasound; however, their medium opacity can limit optimal imaging and depth limitation of 1-4 mm [6][7][8].…”

Section: Introductionmentioning

confidence: 99%

A Contact-Less Electrically Small Antenna Sensor for Retinal Cancer Cell Detection

Rizwan,

Phani Kumar,

Sandeep Kumar

et al. 2023

International Journal of Antennas and Propagation

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A new noninvasive and portable diagnostic system for detecting ocular tumors has been proposed. The system uses a contact-less electrically small antenna sensor to detect retinal cancer cells. The antenna sensor is operated in the ISM (Industrial, Scientific, and Medical) 2.413 GHz band and has electrical dimensions of 8 × 16.2 × 0.35 mm3. The antenna sensor is fabricated on a biodegradable Teslin substrate and tested in an eye-mimicking phantom to compare numerical computations with measurements. The specific absorption rate (SAR) obtained at near and far-field distances under 1 g of tissue is 1.18 W/kg and 0.353 W/kg, and that under 10 g of tissue is 0.112 W/kg and 0.313 W/kg, respectively. Furthermore, to detect the ocular tumor using the proposed antenna sensor, the resonance frequency shift, and the unsupervised machine learning technique, principle component analysis (PCA) is employed on simulated and measured results. The resonance frequency shift for a 3.5 mm radius tumor is 70 MHz for a single tumor and 120 MHz for double tumors. The PCA generates clusters with and without tumors on the positive and negative sides of the two-dimensional plot. The proposed techniques are more impactful in distinguishing between healthy and malignant tissues. The proposed systematic approach could be a portable platform for early detection of cancerous cells inside the eye.

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Translating Intravascular Optical Coherence Tomography from a Research to a Clinical Tool

Phipps

Hoyt

Milner

et al. 2015

Curr Cardiovasc Imaging Rep

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Capabilities, limitations, and misconceptions of using OCT to assess vulnerable plaques

Cited by 6 publications

References 9 publications

Comparing the Risk Factors of Plaque Rupture and Failed Plaque Healing in Acute Coronary Syndrome

Comparing the Risk Factors of Plaque Rupture and Failed Plaque Healing in Acute Coronary Syndrome

A Contact-Less Electrically Small Antenna Sensor for Retinal Cancer Cell Detection

Translating Intravascular Optical Coherence Tomography from a Research to a Clinical Tool

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