Capabilities of an Information-Analytical System for Assessing Motor Activity in Parkinson's Disease During Sleep

Abstract

The research aimed to study motor activity in Parkinson's disease during sleep using a data analytical system developed by authors. The study included 8 patients (4 men and 4 women) diagnosed with Parkinson's disease at the age from 59 to 89 years. All patients were clinically evaluated for motor deficit (UPDRS Part III), motor fluctuations (UPDRS Part IV), functional activity (UPDRS Part I), non-motor symptoms (UPDRS Part II) and the clinical global impression. Using our information-analytical system we obtained data on motor activity during sleep and processed it on the following parameters: number of movements, maximum value of the jerk and motor activity coefficient. For the number of movements, the average value for men was 56.7, for women — 47.2. For the maximum value of the jerk, the average value for men was 22.1 g/s, for women — 16.7 g/s. For motor activity coefficient, the average value for men was 27.7%, for women — 22.3%. Thus, the feasibility of using the information analytical system for assessment of motor activity in Parkinson's disease during sleep and the necessity of studying hypokinetic tremors during sleep has been shown.