Capability of different non‐nutritive feed additives on improving productive and physiological traits of broiler chicks fed diets with or without aflatoxin during the first 3 weeks of life

Abstract

An experiment was conducted to determine whether some non-nutritive feed additives (NNFA) could block the adverse effects of aflatoxin (AF) on growth performance and physiological parameters of Cobb broilers throughout the period from 1 to 21 day of age. There were eight treatments consisting of two levels of AF at 0 and 200 ppb and four NNFA within each AF level. These additives included mannan oligosaccharides (MOS) at 2 g/kg diet, hydrated sodium calcium aluminosilicate (HSCAS) at 2 g/kg diet and Lactobacillus acidophilus (Lac) at 2 g/kg diet. At 21 day of age, five chickens of each treatment were slaughtered to study dressing percentage and relative weight of inner organs and glands. AF had a significant negative effect on body weight gain (BWG), and feed intake, while impairing feed conversion ratio (FCR). Aflatoxin significantly increased percentage liver, lymphocyte (%), monocyte (%), serum triglyceride level, and the aspartate aminotransferase (AST), and alanine aminotransferase (ALT), concentrations while decreasing dressing percentage, intestinal percentage, white blood cells (WBCs), red blood cells (RBCs), haemoglobin (Hgb), packed cell volume (PCV), heterophil (%), heterophil/lymphocyte ratio, total serum protein and serum albumin. Aflatoxin adversely affected the morphology of the liver, bursa and the thymus. There was a significant interaction between AF and NNFA on the relative weights of liver, heart and intestine. Lac completely blocked the negative effects of AF on the percentage liver and the heart and partially on the intestine. In conclusion, Lac was most effective in reversing the adverse effects of AF on growth and FCR and on the percentage, functions and morphology of the liver. Hydrated sodium calcium aluminosilicate also improved the economic traits of broilers but was less effective than Lac and more effective than MOS.

Oxidative Stress in Extrahepatic Tissues of Rats Co-Exposed to Aflatoxin B1 and Low Protein Diet

“…Increased lipid peroxidation in the erythrocytes leads to erythrocytic burst with a concomitant increase in hemolysis; hence, this could account for the low PCV and hemoglobin level observed in this study. Previous studies have shown that AFB1 decreased the PCV and hemoglobin of rabbits ( 41 ) and broiler chicks ( 42 ). Huang et al .…”

In Vitro Activity of Toxin Binders on Aflatoxin B1 in Poultry Gastrointestinal Medium

“…There are also some reports that organic TBs such as live yeast (Saccharomyces cerevisiae), gluco-mannan, mannanoligo-saccharide are effective in binding of AFB1 in feed at feeding trials performed in vivo. It was mentioned that the adverse effects of AFB1 were reduced by the addition of feed glucomannan (Karaman et al, 2005;Uttpatel et al, 2011) and mannanoligo-saccharide (Attia et al, 2013) in in vivo feeding trials. Live yeast strains were found to be efficient in binding of AF after mixing as a feed additive (Dogi et al, 2011).…”

The Effects of Dietary Supplementation of Saccharomyces cerevisiae Fermentation Product During Late Pregnancy and Lactation on Sow Productivity, Colostrum and Milk Composition, and Antioxidant Status of Sows in a Subtropical Climate

“…In the present study, compared with sows from L-THI, sows from H-THI had lesser individual piglet birth weight (P < 0.10). It's reported that dietary supplementation of non-nutritive feed additives improved productive and physiological parameters of livestock (28,29). However, dietary supplementation of SCFP did not affect reproductive performance of sows.…”