Capacitive Sensor Readout Circuit for Organic Substance Analysis

Petrellis, Nikos; Spathis, C.; Georgakopoulou, K.; Birbas, Alexios

doi:10.1016/j.protcy.2013.11.004

Cited by 3 publications

(3 citation statements)

References 8 publications

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“…Despite the simplicity of the proposal, the error in the estimation of C X is lower than that of other more complex readout circuits. These results are obtained for a much larger range of capacities, allowing the new DIC to be used in applications where it was impossible to use this type of circuit until now, as in [9], [10], [12]- [14].…”

Section: Introductionmentioning

confidence: 92%

“…According to this expression, the variation in the value of k with respect to that shown in (9) depends on the relationship between the three resistors. Error decreases as R A and R B increase in value with respect to ro.…”

Section: Error and Uncertainty Analysismentioning

confidence: 99%

“…However, the name of capacitive sensor is reserved for those in which α f = 1 and are the most widely used to measure physical and chemical parameters. Measurements made with these capacitive sensors include liquid levels [5], pressure [6], strain [7], humidity [8], and organic substance analysis [9]. Sensor capacitance in such applications varies from tens of picofarads to just a few nanofarads.…”

Section: Introductionmentioning

confidence: 99%

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Simplifying Capacitive Sensor Readout Using a New Direct Interface Circuit

Hidalgo-López

Castellanos-Ramos

2023

IEEE Trans. Instrum. Meas.

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Direct interface circuits (DICs) are efficient for reading resistive, capacitive, or inductive sensors in digital format. The simplest DICs consist of just a few passive elements that connect a digital processor (DP) to a sensor. When reading capacitive sensors, one or several calibration capacitors and/or several charging and discharging cycles are needed to make the estimation, and the result usually requires complex arithmetic operations. This article presents a new type of capacitive DIC that is simple in terms of hardware, needing only two resistors of known value and the DP in order to make the capacitance estimation. In addition, the reading method requires a single sensor charging and discharging cycle, which reduces acquisition time and power consumption. Two time measurements are taken during the discharge which, through a linear transformation of their subtraction (using two constants stored in the DP), give the value of the capacitance. These arithmetic operations are easily implemented on any DP and consume fewer resources than the divisions required on other capacitive DICs. The design has been tested for a wide range of capacitances (from 100 pF to 561 nF), including the value of several capacitive sensors. The average relative error for the entire range is 0.41%, linearity errors are below 0.3%, and the minimum signal-to-noise ratio value is 64 dB.

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Section: Introductionmentioning

confidence: 92%

Section: Error and Uncertainty Analysismentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Simplifying Capacitive Sensor Readout Using a New Direct Interface Circuit

Hidalgo-López

Castellanos-Ramos

2023

IEEE Trans. Instrum. Meas.

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Rapid ultrasensitive and specific BNP biosensor with LED readout

So,

Torres Quiñones,

Kim

et al. 2024

Biomed Microdevices

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Biosensing for diagnostics has risen rapidly in popularity over the past decades. With the discovery of new nanomaterials and morphologies, sensitivity is being constantly improved enough for reliable detection of trace biomarkers in human samples, like serum or sweat. This precision has enabled detailed research on the e cacy of biosensors. However, current biosensors suffer from reduced speed of operation. To make better use of this sensitivity, the development of a conductometric biosensor with insitu use of an LED display can provide rapid determination of sample results, steadily pushing biosensors toward more clinical, point-of-care (POC) applications. In this research, a simple LED (laser emitting diode) was used for facile optical determination and visual output of an ultrasensitive bio-signal ampli cation circuit was made to interface with a b-type natriuretic peptide (BNP) biosensor. Tuning circuit gain enables an elegant method for adjustable separation of concentrations into 3 discrete categories: sub-threshold, analog, and saturation regions. These regions corresponded to 0 < [C] < 500 pg/mL (LED off), 500 < [C] < 1000 pg/mL (LED varying intensity), and 1000 pg/mL < [C] (LED full intensity). System e cacy was tested using human blood serum samples from University of Pittsburgh Medical Center patients, which were able to be accurately detected and sorted for rapid lo-. determination without need for complex digital elements. Additional speci city testing suggests insigni cant impact of non-target biomarkers.

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Rapid Ultrasensitive and Specific BNP Biosensor with LED Readout

So,

Quiñones,

Kim

et al. 2024

Preprint

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Biosensing for diagnostics has risen rapidly in popularity over the past decades. With the discovery of new nanomaterials and morphologies, sensitivity is being constantly improved enough for reliable detection of trace biomarkers in human samples, like serum or sweat. This precision has enabled detailed research on the efficacy of biosensors. However, current biosensors suffer from reduced speed of operation. To make better use of this sensitivity, the development of a conductometric biosensor with in-situ use of an LED display can provide rapid determination of sample results, steadily pushing biosensors toward more clinical, point-of-care (POC) applications. In this research, a simple LED (laser emitting diode) was used for facile optical determination and visual output of an ultrasensitive bio-signal amplification circuit was made to interface with a b-type natriuretic peptide (BNP) biosensor. Tuning circuit gain enables an elegant method for adjustable separation of concentrations into 3 discrete categories: sub-threshold, analog, and saturation regions. These regions corresponded to 0 < [C] < 500 pg/mL (LED off), 500 < [C] < 1000 pg/mL (LED varying intensity), and 1000 pg/mL < [C] (LED full intensity). System efficacy was tested using human blood serum samples from University of Pittsburgh Medical Center patients, which were able to be accurately detected and sorted for rapid lo-fi. determination without need for complex digital elements. Additional specificity testing suggests insignificant impact of non-target biomarkers.

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Capacitive Sensor Readout Circuit for Organic Substance Analysis

Cited by 3 publications

References 8 publications

Simplifying Capacitive Sensor Readout Using a New Direct Interface Circuit

Simplifying Capacitive Sensor Readout Using a New Direct Interface Circuit

Rapid ultrasensitive and specific BNP biosensor with LED readout

Rapid Ultrasensitive and Specific BNP Biosensor with LED Readout

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