Two-wave with diffuse power (TWDP) is one of the most promising models for the description of small-scale fading effects in 5G networks, which employs mmWave band, and in wireless sensor networks deployed in different cavity environments. However, its current statistical characterization has several fundamental issues. Primarily, conventional TWDP parameterization is not in accordance with the model’s underlying physical mechanisms. In addition, available TWDP expressions for PDF, CDF, and MGF are given either in integral or approximate forms, or as mathematically untractable closed-form expressions. Consequently, the existing TWDP statistical characterization does not allow accurate evaluation of system performance in all fading conditions for most modulation and diversity techniques. In this regard, physically justified TWDP parameterization is proposed and used for further calculations. Additionally, exact infinite-series PDF and CDF are introduced. Based on these expressions, the exact MGF of the SNR is derived in a form suitable for mathematical manipulations. The applicability of the proposed MGF for derivation of the exact average symbol error probability (ASEP) is demonstrated with the example of M-ary PSK modulation. The derived M-ary PSK ASEP expression is further simplified for large SNR values in order to obtain a closed-form asymptotic ASEP, which is shown to be applicable for SNR > 20 dB. All proposed expressions are verified by Monte Carlo simulation in a variety of TWDP fading conditions.