In 1975, the pioneering work of J. E. Mazo showed the potential faster-than-Nyquist (FTN) gain of single-carrier binary signal. If the inter-symbol interference is eliminated by an optimal detector, the FTN single-carrier binary signal can transmit 24.7% more bits than the Nyquist signal without any loss of bit error rate performance, which is known as the Mazo limit. In this paper, we apply sphere decoder (SD) with box optimization (BO) to reduce inter-carrier interference (ICI) in FTN non-orthogonal frequency division multiplexing (FTN-NOFDM) system. Compared with the conventional SD, SD with BO can achieve the same performance to reduce ICI, but its average number of expanded nodes in search process is significantly decreased especially for high-order modulation format, which can reduce the complexity of the receiver. When the bandwidth compression factor α is set to 0.802, the transmission rate of QPSK-modulated FTN-NOFDM is 24.7% faster than the Nyquist rate, and it has almost the same performance as orthogonal frequency division multiplexing (OFDM), which agrees well with the Mazo limit. The QPSK-modulated FTN-NOFDM with α equal to 0.5 (the spectral efficiency is 4 bit/s/Hz) outperforms 16QAMmodulated OFDM by about 1.5 dB. The 16QAM-modulated FTN-NOFDM with α equal to 0.67 and 0.5 (the spectral efficiency is 6 bit/s/Hz and 8 bit/s/Hz, respectively) outperforms 64QAMmodulated and 256QAM-modulated OFDM by about 1.5 dB and 2 dB, respectively. Therefore, FTN-NOFDM will be a promising modulation scheme for the future bandwidth-limited wireless communications.Index Terms-Box optimization, sphere decoder, faster-than-Nyquist, non-orthogonal frequency division multiplexing, intercarrier interference.