Capillary Blood Pressure in Man. Comparison of Direct and Indirect Methods of Measurement. 1

Capillary blood pressure in man. Direct measurements in the digits of normal and hypertensive subjects during vasoconstriction and vasodilatation variously induced

“…A previous study (6) confirmed the observations of Landis (7), that induced increases in local venous pressure were accompanied by rises in capillary blood pressure to values which exceeded the venous pressure.…”

“…In hypertensive states, the capillary blood pressure has been measured (2 to 5), but by indirect methods, the reliability of which has been questioned (6). It seemed advisable, therefore, to study the capillary blood pressure of normal and hypertensive subjects by the accurate, direct, micro-injection method (Landis) (7), and to make the observation not only under resting conditions but also during influences known to alter the circulation in the areas under study.…”

Capillary Blood Pressure in Man. Direct Measurements in the Digits During Induced Vasoconstriction 1

“…The direct micro-injection method (Landis) (3), modified as previously described (4), was used to measure the capillary blood pressure in single capillaries in the nail folds of the fingers. The glass micropipette and the connecting manometer system were filled either with Ringer's solution or with 0.85 per cent sodium chloride solution, each containing heparin (3 mgm.…”

Capillary Blood Pressure in Man. Direct Measurements in the Digits During Arterial Hypertension Induced by Paredrinol Sulfate 1

“…A previous study (1) indicated that the digital capillary blood pressure was approximately equal in both normal and hypertensive subjects, not only during the resting state, but also during physiologically induced vasoconstrictions and vasodilatations. It was the purpose of this investigation to determine what happened to digital capillary blood pressure when hypertension was induced in subjects with normal arterial pressures.…”

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A previous study (1) (1, 2, 3), all determinations of capillary blood pressure were made on capillaries in the nail-folds of the fingers. The direct microinjection method (Landis) (4), modified as previously described (2), was employed.

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