Capillary electrochromatography applied to drug analysis

Fanali, Chiara; Posta, Susanna Della; Fanali, Salvatore

doi:10.1016/j.jcoa.2021.100015

Cited by 12 publications

(1 citation statement)

References 76 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Hence, enantioselective separation and isolation of enantiopure compounds are highly desirable processes 7 . Enantiomer separation is most commonly accomplished by a number of chromatographic techniques including ultrahigh/high performance liquid chromatography (UPLC/HPLC), 8 gas chromatography (GC), 9 thin‐layer chromatography (TLC), 10 micellar chromatography (MC), 11 supercritical fluid chromatography (SFC), 12 high‐speed countercurrent chromatography (HSCCC), 13 and capillary electrochromatography (CEC) 14 . Capillary electrophoresis (CE), 15 crystallization resolution, 16 and membrane separation by kinetic resolution were also applied 17 …”

Section: Introductionmentioning

confidence: 99%

Chirality of proteinoid nanoparticles made of lysine and phenylalanine

Lugasi

Otis

Oliel

et al. 2022

Polymers for Advanced Techs

View full text Add to dashboard Cite

Proteinoid nanoparticles composed of L-lysine and L-phenylalanine were prepared and showed enantioselective adsorption of L-amino acids at various pH values, emphasizing the chiral nature of the particles. The adsorption was examined using circular dichroism, isothermal titration calorimetry and ζ-potential measurements.Positively charged ammonium moieties on the proteinoid surface are most likely responsible for the enantioselective adsorption owing to their chirality which originates from L-lysine. Accordingly, a higher enantiomeric excess was found for amino acids such as alanine with a more negative charge.

show abstract