Capillary electrophoresis–mass spectrometry analysis of bisphenol A and its analogues in bottled tea beverages with dynamic pH focusing

Capillary Electrophoresis: A Three-Year Literature Review

“…Because protons and hydroxides migrate much faster than other ions, the pH junction is wiped out before the separation begins, eliminating the need for nonvolatile electrolytes throughout the injection and separation process . This sample focusing technique has been applied for the analysis of amino acids, peptides, digested monoclonal antibodies (mAbs), de novo mAb sequencing, detection of antibiotics in milk and yogurt, and analysis of bisphenol A and its analogs in bottled tea beverages …”

“…Preconcentration or derivatization assays are usually incorporated in this type of analysis to enhance detection or quantification sensitivities. A CE-MS method was developed for the rapid detection of bisphenol and its analogs in tea beverages . With acid barrage stacking, a 53- to 107-fold increase in average peak area and a LOD down to low ppb level were achieved.…”

“…13 This sample focusing technique has been applied for the analysis of amino acids, peptides, digested monoclonal antibodies (mAbs), 14 de novo mAb sequencing, 15 detection of antibiotics in milk and yogurt, 16 and analysis of bisphenol A and its analogs in bottled tea beverages. 17 Liquid-Phase Extraction Preconcentration. Meng et al demonstrated the effectiveness of dispersive liquid-phase microextraction (DLPME) in the preconcentration of eight drugs of abuse, including 6-monoacetylmorphine, morphine, and codeine, in complex human urine samples.…”

“…A CE-MS method was developed for the rapid detection of bisphenol and its analogs in tea beverages. 17 With acid barrage stacking, a 53-to 107-fold increase in average peak area and a LOD down to low ppb level were achieved. Similarly, a dynamic pH barrage junction stacking method was used for the quantification of sulfonamide, a synthetic broad-spectrum antibiotic in milk and yogurt.…”

Capillary electromigration methods for food analysis and Foodomics: Advances and applications in the period March 2021 to March 2023

“…Finally, an acid plug solution of 0.05% acetic acid in MeOH/water (30:70, v/v, pH 3.6) was applied creating a difference of pH in the capillary to produce the separation of the analytes. This method provided a good linearity as well as LODs (0.03–0.04 ng/mL) for bisphenol A and its analogs determined in bottled tea beverages by CE–MS [94].…”