Capillary magnetophoresis of human blood cells and their magnetophoretic trapping in a flow system

Watarai, Hitoshi; Namba, Makoto

doi:10.1016/s0021-9673(02)00748-3

Cited by 87 publications

(67 citation statements)

References 8 publications

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“…The gap between the pole pieces was 0.8 mm. A large gradient of magnetic field was obtained at the edge of the pole pieces [26]. We defined the direction of gravity as the x-direction and the center of the pole piece as x = 0.…”

Section: Methodsmentioning

confidence: 99%

“…Electromagnetophoresis [17][18][19][20][21][22], which is migration under a homogeneous magnetic field and an electric current, has great potential not only for characterizing microparticles by conductivity measurement, but also for measuring the adhesion force between microparticles in a liquid and the cell wall by measuring desorption current. Magnetophoresis [23][24][25][26][27][28][29][30] can be observed under an inhomogeneous magnetic field. Magnetic susceptibility can be determined from magnetophoretic velocity.…”

Section: Introductionmentioning

confidence: 99%

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Magnetic susceptibility measurement of single iron/cobalt carbonyl microcrystal by atmospheric magnetophoresis

Suwa

Oshino

Watarai

et al. 2008

Science and Technology of Advanced Materials

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In this study, the use of an innovative atmospheric magnetophoresis, which enables us to measure the mass magnetic susceptibility and mass of a microparticle simultaneously, was demonstrated. Using this technique, we determined the magnetic susceptibility of a crystalline deposit of iron/cobalt carbonyl, mainly composed of Fe 2 (CO) 9 , which was prepared photochemically from a gaseous mixture of iron pentacarbonyl (Fe(CO) 5 ) and cobalt tricarbonyl nitrosyl (Co(CO) 3 NO). The mass magnetic susceptibility and the characteristic relaxation time of the microcrystal were (7.0 ± 1.9) × 10 −9 m 3 kg −1 and (5.6 ± 2.2) × 10 −4 s, respectively. The observed magnetic susceptibility shows that the microparticle was paramagnetic. Assuming that the density was equal to that of Fe 2 (CO) 9 (2.1 × 10 3 kg m −3 ) and that the shape of the particle was spherical, a hydrodynamic radius of 4.7 µm and a mass of 0.91 ng were observed. It was suggested that Co was incorporated in Fe 2 (CO) 9 .

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Section: Methodsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Magnetic susceptibility measurement of single iron/cobalt carbonyl microcrystal by atmospheric magnetophoresis

Suwa

Oshino

Watarai

et al. 2008

Science and Technology of Advanced Materials

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“…35,36 The configuration of magnets (Nd-Fe-B) and iron pole pieces is shown in Fig. 12, which could generate a magnetic field gradient toward the flow direction.…”

Section: ·2 Analytical Separation Techniquesmentioning

confidence: 99%

Migration Analysis of Micro-Particles in Liquids Using Microscopically Designed External Fields

et al. 2004

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The recent development of new migration methods of micro-particles in liquids using various external fields is reviewed. The combination of a laser scattering force and a photothermal effect produced photothermal-conversion laserphotophoresis. A dielectric field generated in a planer or a capillary quadrupole electrode realized dielectrophoresis. Using a micrometer-scaled magnetic field gradient, the "Magnetophoretic velocimetry" of micro-particles was invented. Furthermore, the Lorentz force generated by combining an electric field and a magnetic field was utilized for electromagnetophoresis. These new methods were overlooked and the advantages in analytical use were discussed.

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“…1 The magnetophoresis separation of various particles has been studied, which included paramagnetic particles of biological cells bound with magnetic particles, [2][3][4][5][6][7][8][9][10] as well as diamagnetic particles of nucleic acids and proteins, 11 single emulsion droplets, 12 single red blood cell, 13 a dysprosium(III) adsorbed organic droplet, 14,15 a single crystal of Prussian blue analogue, 16 polystyrene particles, 17 polymer beads, 18 bacillus atrophaeus spores, 19 and allergen-specific immunoglobulin E. 20 However, studies on magnetophoretic velocity analysis, which is sometimes called magnetophoretic velocimetry, to determine the particle magnetic susceptibility are still limited. The one-dimensional horizontal-migration magnetophoretic velocity, v, of a spherical particle in a liquid medium, when the density of the particle is not so far from that of the medium, hence the magnetic force, the magnetic buoyancy, and the viscous force on the particle are balanced, is expressed by the next equation: …”

Section: Introductionmentioning

confidence: 99%

Zero-velocity Magnetophoretic Method for the Determination of Particle Magnetic Susceptibility

et al. 2014

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A simple zero-velocity method to determine the particle magnetic susceptibility by measuring the magnetophoretic velocity was proposed. The principle is that the magnetophoretic velocity of a particle in a liquid medium must be zero when the magnetic susceptibilities of the medium and the particle are equal, or the gravity force and the magnetophoretic force are balanced. By changing the medium magnetic susceptibility and measuring the magnetophoretic velocity of a particle, the particle magnetic susceptibility was determined from the medium magnetic susceptibility under the zero-velocity condition. The feasibility of the method was demonstrated for polystyrene particles using a Dy(III) solution in the horizontal migration mode and different organic solvents in the vertical migration mode.

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Capillary magnetophoresis of human blood cells and their magnetophoretic trapping in a flow system

Cited by 87 publications

References 8 publications

Magnetic susceptibility measurement of single iron/cobalt carbonyl microcrystal by atmospheric magnetophoresis

Magnetic susceptibility measurement of single iron/cobalt carbonyl microcrystal by atmospheric magnetophoresis

Migration Analysis of Micro-Particles in Liquids Using Microscopically Designed External Fields

Zero-velocity Magnetophoretic Method for the Determination of Particle Magnetic Susceptibility

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