Capítulo 7 – Tratamento Medicamentoso

Malachias, Mvb; Souza, Wksb; Plavnik, FL; Rodrigues, Cibele Isaac Saad; Brandão, AA; Neves, Mft; Bortolotto, LA; Franco, Rjs; Figueiredo, Cep; Jardim, Pcbv; Amodeo, Celso; Barbosa, Ecd; Koch, Vera H.; Gomes, Mam; Paula, RB; Póvoa, Rms; Colombo, FC; Filho, S Ferreira; Miranda, Roberto Dischinger; Machado, CA; Nobre, Fernando; Nogueira, AR; Júnior, Décio Mion; Kaiser, Sérgio; Forjaz, Clm; Almeida, FA; Martim, Jfv; Sass, Nelson; Drager, LF; Muxfeldt, Elizabeth Silaid; Bodanese, LC; Feitosa, AD; Malta, Deborah Carvalho; Fuchs, Susanne; Magalhães, ME; Oigman, W; Gomes, OM; Pierin, Amg; Feitosa, GS; Bortolotto, Mrfl; Magalhães, Lbnc; Silva, Acs; Ribeiro, JM; Borelli, Fao; Gus, Miguel; Júnior, O Passarelli; Toledo, JY; Salles, GF; Martins, Laura Bezerra; Jardim, Tsv; Guimarães, Icb; Antonello, IC; Júnior, E Lima; Matsudo, Victor; Silva, GV; Costa, LS; Alessi, Alexandre; Scala, Lcn; Coelho, Emerson Filipino; Souza, Dilma do Socorro Moraes de; Lopes, Heno Ferreira; Gowdak, Mmg; Júnior, AC Cordeiro; Torloni,; Klein, Mrst; Nogueira, PK; Lotaif, Lad; Rosito, Gba; Júnior, Heitor Moreno

doi:10.5935/abc.20160157

Cited by 6 publications

(3 citation statements)

References 82 publications

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“…The local health care system has already been structured. No additional cost will be necessary regarding human resources or new buildings and most of the antihypertensive drugs are available at PPP [10] , [18] . Individuals aged ≥ 35 years will be included, so that it will be possible to identify and reduce earlier the risk of cardiovascular disease in hypertensive patients.…”

Section: Discussionmentioning

confidence: 99%

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Matão Controlling Hypertension (MatCH) project: Rationale and design

Minelli¹,

Cabral

Leite³

et al. 2017

Contemporary Clinical Trials Communications

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BackgroundHypertension is the main risk factor for most cardiovascular diseases. A coordinated and organized system from the Brazilian Ministry of Healthy involving Family Health Strategy (FHS), a program for the prevention of chronic disease, and the Popular Pharmacy Program (PPP), which subsidizes medications for the population, could allow an earlier identification and better blood pressure (BP) control. Matão Controlling Hypertension (MatCH) is a community-based population project that aims to apply an organized, integrated and coordinated program in the city of Matão, Brazil, involving FHS and PPP in order to actively search, treat and follow-up hypertensive subjects.MethodThis is a population community-based, interventional, follow-up study where all subjects aged ≥ 40 years assisted by the FHS program in Matão will have BP assessed monthly by trained Community Health Agents (CHA) during a domiciliary visit. Identified hypertensive subjects will be referred to FHS physicians for nonpharmacological and pharmacological treatment. Most of the hypertensive drugs used will be available through the PPP. Prevalence of hypertension, awareness, demographics and risk factors will be correlated with BP control. The population study is expected to involve approximately 18.600 subjects. The study period will be four years.DiscussionConsidering that hypertension is asymptomatic in most cases, to reduce the population burden of BP-related deaths and diseases it is essential to detect and treat early all hypertensive patients. If we achieve our large-scale BP control, this program can be applied to other populations from developing countries.

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Section: Discussionmentioning

confidence: 99%

“…The treatment of hypertension will be based on the recent VII Brazilian Guidelines of Arterial Hypertension [17] , [18] .…”

Section: Methodsmentioning

confidence: 99%

Matão Controlling Hypertension (MatCH) project: Rationale and design

Minelli¹,

Cabral

Leite³

et al. 2017

Contemporary Clinical Trials Communications

View full text Add to dashboard Cite

show abstract

“…2 The regular practice of exercise, mainly aerobic exercises, is highly recommended due to its hypotensive effect. 3 Actually, a single session of exercise is already able to promote a sustained reduction of blood pressure, this phenomenon is called post-exercise hypotension (PEH). 4-6…”

mentioning

confidence: 99%

Group Means and Inter-Individual Analysis in Post-exercise Hypotension: Effects of Citrulline Malate Oral Supplementation

Brito

2019

Arquivos Brasileiros De Cardiologia

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Variation in the Proportion of Adults in Need of Blood Pressure–Lowering Medications by Hypertension Care Guideline in Low- and Middle-Income Countries

et al. 2021

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Background: Current hypertension guidelines vary substantially in their definition of who should be offered blood-pressure-lowering medications. Understanding the impact of guideline choice on the proportion of adults who require treatment will be crucial for planning and scaling up hypertension care in low- and middle-income countries (LMICs). Methods: We extracted cross-sectional data on age, sex, blood pressure, hypertension treatment and diagnosis status, smoking, and body mass index for adults ages 30-70 from nationally representative surveys in 50 LMICs (N = 1,037,215). Our main objective was to determine the impact of hypertension guideline choice on the proportion of adults in need of blood-pressure-lowering medications. We considered four hypertension guidelines: the 2017 American College of Cardiology/American Heart Association (ACC/AHA) guideline, the commonly used 140/90 mmHg threshold, the 2016 World Health Organization HEARTS guideline (WHO), and the 2019 United Kingdom National Institute for Health and Care Excellence (NICE) guideline. Results: The proportion of adults in need of blood-pressure-lowering medications was highest under the ACC/AHA followed by the 140/90, NICE, and WHO guidelines (ACC/AHA: women, 27.7% [95% CI: 27.2%, 28.2%], men, 35.0% [34.4%, 35.7%]; 140/90: women: 26.1% [25.5%, 26.6%], men, 31.2% [30.6%, 31.9%]; NICE: women, 11.8% [11.4%, 12.1%]; men, 15.7% [15.3%, 16.2%]; WHO: women, 9.2% [8.9%, 9.5%], men, 11.0% [10.6%,11.4%]). Individuals who were unaware that they have hypertension were the primary contributor to differences in the proportion needing treatment under different guideline criteria. Differences in the proportion needing blood-pressure-lowering medications were largest in the oldest, 65-69, age group (ACC/AHA: women, 60.2% [58.8%, 61.6%], men, 70.1% [68.8%, 71.3%]; WHO: women, 20.1% [18.8%, 21.3%], men, 24.1.0% [22.3%, 25.9%]). For both women and men and across all guidelines, countries in the European and Eastern Mediterranean regions had the highest proportion of adults in need of blood-pressure-lowering medicines while the South and Central Americas had the lowest. Conclusions: There was substantial variation in the proportion of adults in need of blood-pressure-lowering medications depending on which hypertension guideline was used. Given the great implications of this choice for health system capacity, policymakers will need to carefully consider which guideline they should adopt when scaling up hypertension care in their country.

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Capítulo 7 – Tratamento Medicamentoso

Cited by 6 publications

References 82 publications

Matão Controlling Hypertension (MatCH) project: Rationale and design

Matão Controlling Hypertension (MatCH) project: Rationale and design

Group Means and Inter-Individual Analysis in Post-exercise Hypotension: Effects of Citrulline Malate Oral Supplementation

Variation in the Proportion of Adults in Need of Blood Pressure–Lowering Medications by Hypertension Care Guideline in Low- and Middle-Income Countries

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