1992
DOI: 10.1016/0167-0115(92)91031-t
|View full text |Cite
|
Sign up to set email alerts
|

Capsaicin pretreatment before JP-8 jet fuel exposure causes a large increase in airway sensitivity to histamine in rats

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
4
1

Citation Types

0
11
0

Year Published

1995
1995
2011
2011

Publication Types

Select...
8

Relationship

0
8

Authors

Journals

citations
Cited by 16 publications
(11 citation statements)
references
References 0 publications
0
11
0
Order By: Relevance
“…Further, major alterations in immune function that are long lasting may result in an increased likelihood of development and/or progression of cancer and infectious disease. Kerosene-based petroleum distillates such as jet fuel have been associated with hepatic, renal, neurological and pulmonary toxicity in both animals models and human occupational exposures (Chen et al, 1992; Dossing et al, 1985; Gaworski et al, 1984; Mattie et al, 1991; Pfaff et al, 1993; Pfaff et al, 1995; Struwe et al, 1983; Witten et al, 1990; Witten et al, 1992). Chronic exposure to jet fuel has been shown to cause human liver dysfunction, emotional dysfunction, abnormal electroencephalograms, shortened attention spans, decreased sensorimotor speed (Dossing et al, 1985; Struwe et al, 1983; Knave et al, 1978), and elevations of immunosuppressive serum cytokines (Harris et al, 2007a).…”
Section: Introductionmentioning
confidence: 99%
“…Further, major alterations in immune function that are long lasting may result in an increased likelihood of development and/or progression of cancer and infectious disease. Kerosene-based petroleum distillates such as jet fuel have been associated with hepatic, renal, neurological and pulmonary toxicity in both animals models and human occupational exposures (Chen et al, 1992; Dossing et al, 1985; Gaworski et al, 1984; Mattie et al, 1991; Pfaff et al, 1993; Pfaff et al, 1995; Struwe et al, 1983; Witten et al, 1990; Witten et al, 1992). Chronic exposure to jet fuel has been shown to cause human liver dysfunction, emotional dysfunction, abnormal electroencephalograms, shortened attention spans, decreased sensorimotor speed (Dossing et al, 1985; Struwe et al, 1983; Knave et al, 1978), and elevations of immunosuppressive serum cytokines (Harris et al, 2007a).…”
Section: Introductionmentioning
confidence: 99%
“…Currently, there are no standards for U.S. Air Force personnel exposure to jet fuels of any kind, including JP -8 jet fuel. However, kerosenebased petroleum distillates have been associated with hepatic, renal, neurological and pulmonary toxicity in animals models and human occupational exposures ( Struwe et al, 1983;Gaworski et al, 1984;Dossing et al, 1985;Witten et al, 1990Witten et al, , 1992Mattie et al, 1991;Chen et al, 1992;Pfaff et al, 1993Pfaff et al, , 1995. NAVOSH has recommended that exposures be limited to 350 mg /m 3 over an 8h time period and no more than 1000 mg /m 3 for 15 min.…”
Section: Introductionmentioning
confidence: 99%
“…Animals were then observed for signs of morbidity and mortality, and 2 weeks postinfection the surviving animals were killed for immunological assessment. It should be noted that JP-8 exposure at the levels used in these studies has been shown repeatedly by this laboratory and others to be non-lethal (Harris, et al, 1997a;Hays, et al, 1995;Witten, et al, 1992;Wong, et al, 2004).…”
Section: Discussionmentioning
confidence: 91%
“…Furthermore, major alterations in immune function that are long lasting may result in an increased likelihood of development and/or progression of cancer and infectious disease. Kerosene-based petroleum distillates such as jet fuel have been associated with hepatic, renal, neurological, and pulmonary toxicity in both animal models and human occupational exposures (Struwe, et al, 1983;Gaworski, et al, 1984;Dossing, et al, 1985;Witten, et al, 1990;Mattie, et al, 1991;Witten, et al, 1992;Chen, et al, 1992;Pfaff, et al, 1993Pfaff, et al, , 1995. Both military and commercial aircraft workers are at risk of inhalation toxicity from jet fuels, as aircraft refueling results in the production of significant amounts of aerosolized jet fuel, despite vapor ventilation (Hays, et al, 1995).…”
Section: Introductionmentioning
confidence: 99%