Capsular Contracture and Steroid-Related Complications After Augmentation Mammaplasty A Preliminary Study

An Innovative Procedure for the Treatment of Primary and Recurrent Capsular Contracture (CC) Following Breast Augmentation

“…2 Moreover, despite initial excellent results observed with steroidcontaining inflatable prostheses, at least over a short period, significant dose-related complications-including prosthesis ptosis, atrophy, thinning of overlying breast tissue, impending extrusion, and even CC-have been observed many years after implantation. 56,57 It is worth mentioning, however, that the rapid-acting, water-soluble methylprednisolone sodium succinate we have used immediately and 3 days later (instead of the previously described injection of longer-acting, practically insoluble triamcinolone acetonide 6-8 weeks after surgery) may have affected GC distribution and diffusion in the pocket. In fact, with the mostly used textured implants, strong adhesions form between the capsule and the implant membrane that make uniform distribution of the injected GC unlikely, invariably leading to GC pooling at the injection site and an increased complication rate.…”

The effect of liposome‐delivered prednisolone on collagen density, myofibroblasts, and fibrous capsule thickness around silicone breast implants in rats

“…There are numerous reports of GCs being implanted in local depots 13–18 . However, the steroid doses needed for therapeutic effects in the treatment or prevention of capsule contracture have resulted in adverse effects, impairing their current use.…”

Faut-il drainer après la mise en place d’implants mammaires en position pré-pectorale ? Analyse d’une cohorte de 400 patientes opérées pour augmentation mammaire par implant en gel de silicone en position pré-pectorale

“…Son taux varie de 1 à 6 % selon les études [5,8]. Son existence peut être à l'origine d'une infection ou d'une coque péri-prothétique secondaire affirmée par des auteurs [6,9]. On constate cette complication le plus souvent dans les 24 heures postopéra-toires.…”