“…Receptor unknown, sialic acid and HLA class 1 involvement [113,114] Divergence from BCoV in 1890 [115] Ciliated airway epithelial cells [116], macrophages in culture [117], neuronal cells [118] Upper respiratory infection, GI infection, pneumonia [119] 229E Aminopeptidase N [120] Divergence in 1700-1800 [121], divergence from NL63 in the eleventh century [122] Non-ciliated airway epithelial cells [116], human monocytes [123], neuronal cells [118] Upper respiratory infection [124], GI infection, pneumonia [125] NL63 Ace2 [126] Discovered in 2004 [4], divergence between 1200 and 1500 [127] Ciliated airway epithelial cells [116] Upper and lower respiratory infection [6,128], associated with croup in children [129]…”