Características Sociodemográficas E Reprodutivas De Mulheres Com Câncer De Mama

Freitas, Sabrina Ribas; Petter, Gustavo do Nascimento; Martins, Thais Nogueira de Oliveira; Santos, Luana Farias dos; Porolnik, Sinara; Cielo, Adriana; Vizzotto, Betina Pivetta; Pivetta, Hedionéia Maria Foletto

doi:10.22533/at.ed.4502028092

Cited by 1 publication

(1 citation statement)

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“…The sample included women with confirmed malignancy by anatomopathological report issued after surgery, who underwent adjuvant treatment at Cancer Research Center (CEPON) in Florianopolis/SC, Brazil. The exclusion criteria were: women without confirmed malignancy; previous history of cancer or surgery in a period shorter than one year; women who had undergone neoadjuvant treatment; pregnancy or lactation; women positive for human immunodeficiency virus [27]. From the 139 women recruited at baseline, there were 70 with a full set of data who signed the written consent who were included in this study, after some losses (Figure 1).…”

Section: Study Design Sampling and Ethicsmentioning

confidence: 99%

Dietary Antioxidant Capacity Promotes a Protective Effect against Exacerbated Oxidative Stress in Women Undergoing Adjuvant Treatment for Breast Cancer in a Prospective Study

et al. 2021

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Breast cancer (Bca) is the most common type of cancer among women worldwide, and oxidative stress caused by adjuvant treatment may be decreased by antioxidant intake. The aim of this study is to investigate the associations between Dietary antioxidant Capacity (DaC) and oxidation and antioxidant biomarkers in women undergoing adjuvant treatment (AT) for Bca. This prospective study had a sample of 70 women (52.2 ± 10.7 y). DaC (mmol/g) was calculated using nutritional data obtained from a Food Frequency Questionnaire, and blood was collected to measure the oxidation and antioxidant biomarkers at baseline (T0), and after AT (T1). Carbonylated protein levels were inversely associated with DaC at T1 (p = 0.004); women showed an increased risk of having increment on lipid hydroperoxides and thiobarbituric acid reactive substances (TBARS), and decrement on ferric reducing antioxidant power (FRAP) and reduced glutathione after AT, in response to lowered DaC (p < 0.05). Carbonylated proteins, TBARS and FRAP levels remained stable between the periods for women at the 3rd DaC tertile at T1, differentiating them from those at the 1st tertile, who showed negative changes in these biomarkers (p < 0.04). DaC may be beneficial for women undergoing AT for Bca, since it promoted a reduction in oxidative stress.

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Section: Study Design Sampling and Ethicsmentioning

confidence: 99%