Caractéristiques épidémiologiques, cliniques, histo-pathologiques et thérapeutiques du Cancer du rein dans l’Ouest Algérien: à propos de 115 cas

Harir, Noria; Zeggai, Soumia; Sabri, H.; Mehani, Z.; Tou, Abdenacer

doi:10.1016/j.afju.2016.03.011

Cited by 2 publications

(4 citation statements)

References 9 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The number of cases recorded in our series during the periods 2012-2017 is 55 cases but only 50 files were retained, several files were unusable. This incidence is comparable to that reported in Senegal by Fall et al [7] who had found 8.5 But much lower than that reported in Algeria by Harira et al [3] or 14.3. The increase in frequency and incidence could be explained with the development of medical imaging methods which made the diagnosis of kidney cancer easier.…”

Section: Discussionsupporting

confidence: 82%

See 1 more Smart Citation

Adult Kidney Cancer in Mauritania: Clinical and Therapeutic Aspects

Beya,

Tfeil,

Traore

et al. 2023

OJU

View full text Add to dashboard Cite

Introduction: since its creation, our urology department has taken care of tumor pathologies in particular kidney cancer in adults; our goal is to study the clinical and therapeutic epidemiological profiles of adult kidney cancer in Mauritania. Materials and Methods: We carried out a retrospective study over a period of six years, from January 1, 2012 to December 31, 2017, including all cases of adult kidney cancer registered in the urology-andrology departments of the Cheikh Zayed Hospital and Pathological Anatomy of the National Hospital of Nouakchott (Mauritania). Results: we collected 50 cases of kidney cancer. The average annual incidence was 8.3 cases. The average age of the patients was 52.98 years with extremes of 18 and 84 years. There was a female predominance (52%) or 29 women for 21 men. Lumbar pain was the most frequent clinical expression, more than half of the patients had symptoms over a period of at least 12 months before the first consultation. The left kidney was the most frequently affected. The right localization was demonstrated in 23 patients, the extension assessment was made with thoraco-abdomino-pelvic CT in 40 patients. Twelve patients had a tumor localized in the kidney. The extension assessment had made it possible to objectify the existence of metastases in 17 of our patients (37%). The preferred locations of these metastases were pulmonary and hepatic. Surgical intervention was performed in 44 patients (88%), of whom 36 underwent radical nephrectomy (72%), and two patients underwent partial nephrectomy (4.5%). Surgical abstention was decided from the outset in 6 patients (13.6%). None of our patients had received treatment with anti-angiogenics. The histological type most observed in our patients was renal cell carcinoma, observed in 34 patients, or 77.72%. At the time of the study, more than a third of the patients had died. The mortality rate in our series had reached 24%. A specific survival rate could not be assessed due to lack of information in the files and signifi-

show abstract

Section: Discussionsupporting

confidence: 82%

“…The sex ratio is approximately two men to a woman. The median age at diagnosis is 67 years in men and 70 years in women [2] [3].…”

Section: Introductionmentioning

confidence: 99%

Adult Kidney Cancer in Mauritania: Clinical and Therapeutic Aspects

Beya,

Tfeil,

Traore

et al. 2023

OJU

View full text Add to dashboard Cite

show abstract

“…It was also reported that LC is generally diagnosed at an advanced stage and occurs exponentially in late middle and older age and that NSCLC is the most common type, particularly with the adenocarcinoma sub-type [ 12 ]. In contrast, it was reported that in a province in northwest Algeria, the squamous cell carcinoma was the most common histological type [ 13 ]. Concerning causes of LC occurrence, it was indicated that active and passive smoking constitutes the main risk factor in the addition of professional exposure.…”

Section: Discussionmentioning

confidence: 99%

“…LC is essentially caused by tobacco and other environmental factors and is diagnosed at an advanced stage (II and IV) with different symptoms such as chest pain, cough and so forth. [ 13 , 15 ].…”

Section: Discussionmentioning

confidence: 99%

Clinico-epidemiological profile and redox imbalance of lung cancer patients in Algeria

Otsmane¹,

Kacimi²,

Adane³

et al. 2018

JMedLife

View full text Add to dashboard Cite

Hypothesis: How are the epidemiologic repartition and the physiopathology of lung cancer (LC) in Algeria?Objective: Our study aimed to establish the clinico-epidemiological profile and evaluate redox imbalance in Algerian patients with LC.Methods and results: Our study concerned 94 Algerian patients with LC treated at two hospitals of Algiers, the capital of Algeria. The clinico-epidemiological profile was established. Moreover, the redox imbalance was evaluated by dosing oxidative stress (OS) parameters in tumor tissues and blood. We noted that the average age was 62.06 years, and 79 among the 94 patients were male, 94.59% of which were smokers. The most common histological type was adenocarcinoma (45.45% of cases), followed by squamous cell carcinoma (37.88%) small-cell carcinoma (4.86%) and other histological types (6.67%), while the most frequent clinical stage was IV (66.95 %). 23 of the 94 patients were exposed to particular risk factors such as masonry products, metal mechanics, coal smoke and so forth. In other respects, the OS parameters: NO (Nitrogen monoxide), AOPP (Advanced Oxidation Protein Products) and MDA (Malondialdehyde) were higher in tumor tissues compared to peritumoral stroma (control), unlike the catalase activity. Otherwise, AOPP and MDA were significantly higher in patients’ blood than in healthy control blood, in contrast to the catalase activity.Discussion: The LC has a heterogeneous repartition regarding the sex, age, histological types, the smoking status and professional exposition to risk factors in the Algerian population. Moreover, the oxidative stress impacts the physiopathology of LC.

show abstract

Caractéristiques épidémiologiques, cliniques, histo-pathologiques et thérapeutiques du Cancer du rein dans l’Ouest Algérien: à propos de 115 cas

Cited by 2 publications

References 9 publications

Adult Kidney Cancer in Mauritania: Clinical and Therapeutic Aspects

Adult Kidney Cancer in Mauritania: Clinical and Therapeutic Aspects

Clinico-epidemiological profile and redox imbalance of lung cancer patients in Algeria

Contact Info

Product

Resources

About