CARACTERIZAÇÃO EPIDEMIOLÓGICA DOS CASOS DE COVID-19 NO MARANHÃO: Uma breve análise

Almeida, Joelson dos Santos; Cardoso, Jonas Alves; Cordeiro, Eduardo Costa; Lemos, Messias; Araújo, Telma Maria Evangelista de; Sardinha, Ana Hélia de Lima

doi:10.1590/scielopreprints.314

Cited by 26 publications

(25 citation statements)

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“…In our demographic analysis we found a predominance of females in both groups (cases and controls). This corroborates with the profile found in other studies published in Brazil [30] whereas in Wuhan, China, 56% of the cases were male individuals [31]. It is emphasized that Brazilian population estimative for 2020 shows a slight female dominance [32].…”

Section: Discussionsupporting

confidence: 90%

Higher frequency of hepatic steatosis at CT among COVID-19-positive patients

et al. 2020

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Purpose Recent studies have demonstrated that obesity is significantly associated with increased disease severity, hospitalizations and mortality in COVID-19, with a potential role in the pathogenesis and prevalence in the new pandemic. The association with hepatic steatosis, however, a condition closely related to obesity within the spectrum of systemic metabolic dysfunctions, remains to be elucidated. We aimed to evaluate the frequency of hepatic steatosis as incidentally detected in chest CT examinations of COVID-19 positive patients in comparison to non-infected controls. Methods A retrospective study was performed with 316 patients (204 RT-PCR positive; 112 RT-PCR negative and chest CT negative). Steatosis was measured with placement of a single ROI in the right lobe of the liver (segments VI-VII) and defined as a liver attenuation value ≤ 40 HU. Results The frequency of hepatic steatosis was higher in the RT-PCR positive group in comparison to controls (31.9% vs. 7.1%, p < 0.001). Logistic linear regression analysis showed a 4.7 times odds of steatosis in the COVID-19 positive group as compared to controls after adjusting for age and sex (OR 4.698; 95% IC 2.12-10.41, p < 0.001). Conclusion A significantly higher prevalence of steatosis was found among COVID-19 positive individuals. These findings are in accordance with other recent studies linking obesity and COVID-19 infection, as there is an intricate relationship between liver steatosis, metabolic syndrome and obesity. Further studies are required to confirm if such association remains after accounting for multiple variables, as well as possible relationships with disease severity and worst clinical outcomes.

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Section: Discussionsupporting

confidence: 90%

Higher frequency of hepatic steatosis at CT among COVID-19-positive patients

et al. 2020

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“…Regarding the age group, there was a predominance of cases of patients between 30 and 49 years old for both tests, molecular and serological, for the detection of SARS-CoV-2. Those findings are similar to the ones found in a study carried out in Maranhão (28.4%) 16 and in Wenzhou (China), which presented 58.9% of cases in that same age group 17 . Likewise, individuals aged 30 to 59 years were more prevalent among the cases studied in Rio de Janeiro 10 .…”

Section: Discussionsupporting

confidence: 91%

“…According to the Epidemiological Bulletin of the State of Mato Grosso, the profile of patients with COVID-19 is predominantly female (52%), as well as the prevalence of deaths is also higher in women (59.3%). However, this distribution differs between the states, as in Maranhão the predominance of deaths by COVID-19 was male (62%) 16 . It is believed that women seek health services more frequently than men, and there may be underreporting of cases in the male population, as, historically, men seek health services less, which can lead to the worsening of the disease, late treatment and evolution to death.…”

Section: Discussionmentioning

confidence: 92%

PREVALENCE OF MOLECULAR AND SEROLOGICAL TESTS OF THE NEW CORONAVIRUS (SARS-CoV-2) IN CARLOS CHAGAS-SABIN LABORATORIES IN CUIABÁ

Paula

Passos

Shimoya-Bittencour

et al. 2020

Preprint

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BACKGROUND: COVID-19, the disease caused by the new coronavirus (SARS-CoV-2), became a pandemic in 2020 with mortality rate of 2% and high transmissibility, which makes studies with an epidemiological profile essential. OBJECTIVES: To characterize the population that performed the SARS-CoV-2 molecular and serological tests in Carlos Chagas-Sabin laboratories in Cuiaba. METHODS: A retrospective cross-sectional study was carried out with all the samples collected from nasal swab tested by RT-PCR and serological for SARM-CoV-2 IgM / IgG from the population served between April and July 2020. FINDINGS: In the analyzed period, 11,113 PCR-Covid-19 exams were registered. Of this total of cases, 3,912 (35.20%) tested positive, while 6,889 (61.90%) did not detect viral RNA and 312 (2.80%) of the visits resulted as undetermined. The peak of positive RT-PCR performed in July (n = 5878), with 35.65% (n = 2096). A total of 6,392 tests performed on SOROVID-19, with a peak of 1161 (18.16%) of the positive tests for SARS-CoV-2 in July. MAIN CONCLUSIONS: Molecular positivity and serological tests, both peaked in July 2020, were mostly present in women aged 20-39, characterizing Cuiaba as the epicenter of the Midwest region in this period due to the high rate of transmissibility of SARS- CoV-2. Key words: coronavirus; PCR-RT; serology; IgG; IgM.

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“…In a study carried out in Maranhão, from February 28 to March 19, 2020, of 100 people who died from COVID-19, 62% were male and with respect to age group, 66% of cases were people with 60 years or more (Almeida et al, 2020). Goh et al (2020) also discussed the relationship between age group and deaths from COVID-19.…”

Section: Resultsmentioning

confidence: 99%