Caracterización clínica, funcional y hemodinámica de la población con hipertensión pulmonar arterial evaluada en el Instituto Nacional del Tórax

B, Mónica Zagolín; G, Eduardo Wainstein; C, Polentzi Uriarte G. De; R, Claudio Parra

doi:10.4067/s0034-98872006000500007

Cited by 5 publications

(9 citation statements)

References 13 publications

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“…The Argentinean registries reported similar proportion of patients with functional class III or IV (ranging from 58 to 70%) [21, 22, 29]. One Chilean study [27] with 27 group 1 PH patients showed the highest proportion of patients with severe functional class (85%). Despite the differences, these values are considered high and demonstrate that most of the patients were in an advanced stage of the disease.…”

Section: Resultsmentioning

confidence: 94%

“…The other two excluded publications were conducted in Argentina and described only the study protocol and methodology of the HINPULSAR [23] and the RECOPILAR registries [24] but did not report results. Four articles were included in the final analysis: two Chilean [27, 28] one Argentinean [29] and one Brazilian [7]. The characteristics of the PAH registries are provided in Table 1.…”

Section: Resultsmentioning

confidence: 99%

“…All the studies included just adult patients, except the Argentinean by Talavera et al, [29] that included 16 patients (12.8%) younger than 18 years. All studies reported greater frequency of PAH in female patients ranging from 60% [28] up to 86% [27], both values found in small cohorts in Chile.…”

Section: Resultsmentioning

confidence: 99%

“…Only one of the Argentinean studies [29] and one of the Chilean studies [27] reported the time from onset of symptoms to diagnosis (1.4 and 2.9 years, respectively).…”

Section: Resultsmentioning

confidence: 99%

“…Mean right atrial pressure (RAP) ranged from 8 in the Chilean [27] and Argentinean [29] registries up to 12 ± 8 mmHg in the Chilean study [28]. The mean pulmonary artery pressure (mPAP) ranged from 52 ± 18 mmHg in the Brazilian study [7] up to 59 ± 12 mmHg in Chile [27]. Regarding the pulmonary vascular resistance (PVR), only the Brazilian [7] and the Argentinean [29] registries reported this parameter and it was similar (10 ± 6 and 12 woods units, respectively).…”

Section: Resultsmentioning

confidence: 99%

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Pulmonary arterial hypertension in Latin America: epidemiological data from local studies

et al. 2018

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BackgroundPulmonary arterial hypertension is a rare, progressive disease with poor prognosis. However, there is limited information available on the characteristics of PAH patients outside of North America and Europe. This is particularly important as researchers have described that there are potential geographical and regional differences which are vital to consider in the design of clinical trials as well as PAH treatment. The aim of this study was to describe the epidemiology of PAH (PH group 1) in Latin America.MethodsA search of electronic databases for studies published in English, Spanish or Portuguese was conducted specifying publication dates from the 1st of January 1987 until 10th October 2016. Two authors independently assessed papers for inclusion and extracted data. A narrative synthesis of the findings was conducted.ResultsThe search revealed 22 conference abstracts and articles, and on application of the inclusion criteria, six conference abstracts and articles were included in the final review. Studies/registries were based in Argentina, Brazil and Chile. In contrast to the available literature from developed countries, in Latin America, most patients were diagnosed at younger age; nevertheless, the higher prevalence of idiopathic PAH (IPAH) and the advanced stage of the disease at diagnosis were comparable to the existing literature, as the long term survival, despite the lower availability of targeted therapies.ConclusionThis study highlights the regional characteristics in the epidemiology of group 1 PH. The recognition of these differences should be considered when developing clinical guidelines and extrapolating diagnostic and treatment algorithms. Equitable access to health care and therapies are also issues that need to be addressed in Latin America. Information coming from a large prospective registry representing the different populations in Latin America is of critical importance to increase disease awareness in the region and improve diagnosis and management.Electronic supplementary materialThe online version of this article (10.1186/s12890-018-0667-8) contains supplementary material, which is available to authorized users.

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Section: Resultsmentioning

confidence: 94%

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

“…Only one of the Argentinean studies [29] and one of the Chilean studies [27] reported the time from onset of symptoms to diagnosis (1.4 and 2.9 years, respectively).…”

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

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Pulmonary arterial hypertension in Latin America: epidemiological data from local studies

et al. 2018

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Hipertensión Pulmonar: Importancia De Un Diagnóstico Precoz Y Tratamiento Específico

Zagolin

Llancaqueo

2015

Revista Médica Clínica Las Condes

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Palabras clave: Hipertensión pulmonar, diagnóstico precoz, tamizaje ecocardiográfico, terapia, repuesta a la terapia. SUMMARYPulmonary arterial hypertension (PAH) is a chronic disease, characterized by increased pulmonary vascular resistance (PVR) at the pulmonary arterioles, which causes a progressive overload and subsequent dysfunction of the right ventricle (RV), which final stages leading to right heart failure, which

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Disfunción grave de ventrículo derecho por ecocardiografía en hipertensión arterial pulmonar: prevalencia, predictores clínicos, ecocardiográficos y tratamiento

Cursack¹

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La DGVD es un reconocido marcador pronóstico en HAP, enfermedad de baja prevalencia pero de mal pronóstico. El tratamiento específico y precoz de esta patología permite mejorar su sobrevida, a un alto costo. El ecocardiograma Doppler nos permitirá, seleccionando los pacientes con DGVD y otros parámetros ecocardiográficos, identificar variables epidemiológicas, clínicas y de tratamiento para ofrecer mejores recursos a los pacientes que más se benefician.

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Caracterización clínica, funcional y hemodinámica de la población con hipertensión pulmonar arterial evaluada en el Instituto Nacional del Tórax

Abstract: This group of patients with Pulmonary Arterial Hypertension was mainly conformed by young females, with a moderate to severe disease.

Cited by 5 publications

References 13 publications

Pulmonary arterial hypertension in Latin America: epidemiological data from local studies

Pulmonary arterial hypertension in Latin America: epidemiological data from local studies

Hipertensión Pulmonar: Importancia De Un Diagnóstico Precoz Y Tratamiento Específico

Disfunción grave de ventrículo derecho por ecocardiografía en hipertensión arterial pulmonar: prevalencia, predictores clínicos, ecocardiográficos y tratamiento

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