Caracterización de aislamientos de Cryptococcu s en Uruguay

Carbia, Mauricio; Perera, Patricia; Arteta, Zaida; Cabeza, Elisa; Ballesté, Raquel; Gezuele, E.

doi:10.1016/j.riam.2016.05.006

Cited by 4 publications

(2 citation statements)

References 4 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Ten percent of them (17/162) developed cryptococcosis at some point during follow up, and for 3% (5/172) this infection was the first disease indicating AIDS [ 13 ]. More recently, a laboratory based study reported 147 cases of cryptococcosis (including 135 form HIV patients, 1 from an immunocompetent person, and 1 from a non-HIV immunocompromised patient) from different country regions over six years, between 2006 and 2012 [ 14 ]. Based on this last report, assuming that all the isolates from invasive cryptococcosis were received by the author and each represents a different episode, we can estimate about 25 cases/year, which would represent an annual incidence of 2.1/1000 HIV patients and 0.73/100,000 inhabitants.…”

Section: Resultsmentioning

confidence: 99%

Estimating the Burden of Serious Fungal Infections in Uruguay

Macedo-Viñas

Denning

2018

JoF

View full text Add to dashboard Cite

We aimed to estimate for the first time the burden of fungal infections in Uruguay. Data on population characteristics and underlying conditions were extracted from the National Statistics Institute, the World Bank, national registries, and published articles. When no data existed, risk populations were used to estimate frequencies extrapolating from the literature. Population structure (inhabitants): total 3,444,006; 73% adults; 35% women younger than 50 years. Size of populations at risk (total cases per year): HIV infected 12,000; acute myeloid leukemia 126; hematopoietic stem cell transplantation 30; solid organ transplants 134; COPD 272,006; asthma in adults 223,431; cystic fibrosis in adults 48; tuberculosis 613; lung cancer 1400. Annual incidence estimations per 100,000: invasive aspergillosis, 22.4; candidemia, 16.4; Candida peritonitis, 3.7; Pneumocystis jirovecii pneumonia, 1.62; cryptococcosis, 0.75; severe asthma with fungal sensitization, 217; allergic bronchopulmonary aspergillosis, 165; recurrent Candida vaginitis, 6323; oral candidiasis, 74.5; and esophageal candidiasis, 25.7. Although some under and overestimations could have been made, we expect that at least 127,525 people suffer from serious fungal infections each year. Sporothrichosis, histoplasmosis, paracoccidioidomycosis, and dermatophytosis are known to be frequent but no data are available to make accurate estimations. Given the magnitude of the burden of fungal infections in Uruguay, efforts should be made to improve surveillance, strengthen laboratory diagnosis, and warrant access to first line antifungals.

show abstract

Section: Resultsmentioning

confidence: 99%

Estimating the Burden of Serious Fungal Infections in Uruguay

Macedo-Viñas

Denning

2018

JoF

View full text Add to dashboard Cite

show abstract

“…Ten percent of them (17/162) developed cryptococcosis at some point during follow up, and for 3% (5/172) this infections was the first disease indicating AIDS [13]. More recently a laboratory based study reported 147 cases of cryptococcosis (including 135 form HIV patients, 1 from an immunocompetent person and 1 from a non-HIV immunocompromised patient) from different country regions over 6 years, between 2006 and 2012 [14]. Based on this last report, assuming that all the isolates from invasive cryptococcosis were received by the author and each represents a different episode, we can estimate an annual incidence of 0.71/100,000 (25 cases/year).…”

Section: Resultsmentioning

confidence: 99%