Carbamazepine

Dickinson, R. G.; Eadie, Mervyn J.; Vajda, Eric

doi:10.1007/978-3-642-60072-2_10

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Pharmacokinetics1

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2014

2022

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Cited by 3 publications

(1 citation statement)

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“…This has a shorter half-life than carbamazepine, thus, in continued use, its plasma concentrations tend to parallel those of the parent substance. The epoxide is hydrolysed to a biologically inactive diol derivative, excreted mainly as a glucuronide conjugate (figure 4) (Dickinson et al, 1999).…”

Section: Pharmacokineticsmentioning

confidence: 99%

The clinical pharmacology of traditional antiepileptic drugs

Vajda

Eadie

2014

Epileptic Disorders

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Despite the availability of newer agents, a number of antiepileptic drugs have continued to be employed reasonably widely, many years after their introduction to human therapeutics. These drugs comprise phenobarbitone and some of its congeners, phenytoin, ethosuximide, carbamazepine, valproate, and certain benzodiazepines. Details of their pharmacological profiles are outlined in the following account.

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Section: Pharmacokineticsmentioning

confidence: 99%