Carbocyclic Galanthamine Analogues: Incorporating the Phenethylamine Motif.

Abstract

Alkaloids Alkaloids U 0600Carbocyclic Galanthamine Analogues: Incorporating the Phenethylamine Motif.-An unnatural analogue of the anti-Alzheimer drug galanthamine bearing a phenethylamine moiety is prepared as a racemic mixture using K 3 [Fe(CN) 6 ]-induced tandem cyclization techniques as the key step to form derivatives of the novel 6H-benzo[a]cyclohepta[hi]benzofuran ring system. -(TREU, M.; MEREITER, K.; HAMETNER, C.; FROEHLICH, J.; JORDIS*, U.; J.