2012
DOI: 10.3945/ajcn.111.031641
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Carbohydrate nutrition is associated with changes in the retinal vascular structure and branching pattern in children

Abstract: Greater consumption of carbohydrates and soft drinks was associated with retinal arteriolar narrowing and venular widening. Because these microvascular signs have been shown to be markers of future cardiovascular disease risk, the presence of this risk factor in children could support the need for healthy dietary patterns that include lower consumption of high-GI foods and soft drinks.

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Cited by 34 publications
(42 citation statements)
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“…Covariates that were found to be significantly associated with retinal vessel caliber [19] were included in multivariable models: age, sex, ethnicity, total energy intake, axial length of the eye, BMI, MABP and fellow vessel caliber (i.e. venular caliber adjusted in model for arteriolar caliber and vice versa).…”
Section: Discussionmentioning
confidence: 99%
“…Covariates that were found to be significantly associated with retinal vessel caliber [19] were included in multivariable models: age, sex, ethnicity, total energy intake, axial length of the eye, BMI, MABP and fellow vessel caliber (i.e. venular caliber adjusted in model for arteriolar caliber and vice versa).…”
Section: Discussionmentioning
confidence: 99%
“…As fractal dimension is a ratio, rather than an absolute measurement, it is not affected by the effect of magnification [37]. Retinal fractal dimensions have previously been shown to be affected by blood pressure [15] and nutrition [38], but not by body mass index [39]. Smaller retinal fractal dimensions have been observed in children with higher blood pressure, leading researchers to hypothesize that this change may reflect rarefaction of the microvasculature [15].…”
Section: Discussionmentioning
confidence: 99%
“…28 In this study, we examined the associations of physical activity, TV viewing time, and time spent playing computer and video games with retinal vascular caliber in a cohort of Australian children and adolescents with type 1 diabetes. We hypothesized that more time spent engaging in sedentary behaviors and lower levels of physical activity would be associated with alterations in retinal vascular caliber.…”
Section: Discussionmentioning
confidence: 99%