Carbohydrate polymer-based silver nanocomposites: Recent progress in the antimicrobial wound dressings

Rahimi, Mahdi; Noruzi, Ehsan Bahojb; Baghi, Hossein Bannazadeh; Ebadi, Baharin; Kariminezhad, Zahra; Molaparast, Morteza; Mehrabani, Mojtaba Ghanbari; Mehramouz, Bahareh; Yousefi, Mehdi; Ahmadi, Raman; Yousefi, Bahman; Ganbarov, Khudaverdi; Kamounah, Fadhil S.; Shafiei‐Irannejad, Vahid; Kafil, Hossein Samadi

doi:10.1016/j.carbpol.2019.115696

Cited by 145 publications

(75 citation statements)

References 178 publications

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“…This dimension could completely meet the requirements for antimicrobial applications which need the nanoparticles being less than 100 nm. At this scale, the nanoparticles can penetrate into the microorganism membranes to inhibit their growth through interacting with many kinds of proteins, DNA and enzymes [7,8].…”

Section: The Size and Morphology Of Mcagnps And Pgagnpsmentioning

confidence: 99%

“…About dose as well as inhibitory effect, the MC.AgNPs and PG.AgNPs were corresponded with those commercial AgNPs. In case of an antimicrobial mechanism, silver nanoparticles were degraded in biologically reducing media to release Ag + ions interacting the proteins of cell membranes or inside cell walls that led to inhibit cell division or cause cell dead [8]. Thus these MC.AgNPs and PG.AgNPs covered with naturally organic functional groups might achieve the long-term biodegradation as well as the sustainable release of Ag + ions in vivo.…”

Section: Antifungal Activity Of Mcagnps and Pgagnpsmentioning

confidence: 99%

“…By exploiting this route, the biogenic AgNPs were able to be formed within the range less than 100 nm. These sizes facilitate AgNPs to go through the bacteria/fungi walls and damage membranes as well as to release Ag + to disturb some mechanisms in cells [7,8]. In addition, phytochemicals not only could stabilize AgNPs but also act as an effective molecules in antimicrobial activities [7].…”

Section: Introductionmentioning

confidence: 99%

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Comparison of biogenic silver nanoparticles formed by Momordica charantia and Psidium guajava leaf extract and antifungal evaluation

Nguyen

et al. 2020

PLoS ONE

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Exploiting plant extracts to form metallic nanoparticles has been becoming the promising alternative routes of chemical and physical methods owing to environmentally friendly and abundantly renewable resources. In this study, Momordica charantia and Psidium guajava leaf extract (MC.broth and PG.broth) are exploited to fabricate two kinds of biogenic silver nanoparticles (MC.AgNPs and PG.AgNPs). Phytoconstituent screening is performed to identify the categories of natural compounds in MC.broth and PG.broth. Both extracts contain wealthy polyphenols which play a role of reducing agent to turn silver (I) ions into silver nuclei. Trace alkaloids, rich saponins and other oxygen-containing compounds creating the organic corona surrounding nanoparticles act as stabilizing agents. MC.AgNPs and PG. AgNPs are characterized by UV-vis and FTIR spectrophotometry, EDS and TEM techniques. FTIR spectra indicate the presence of O-H, C = O, CO -C and C = C groups on the surface of silver nanoparticles which is corresponded with three elements of C, O and Ag found in EDS analysis. TEM micrographs show the spherical morphology of MC.AgNPs and PG.AgNPs. MC.AgNPs were 17.0 nm distributed in narrow range of 5-29 nm, while the average size of PG.AgNPs were 25.7 nm in the range of 5-53 nm. Further, MC.AgNPs and PG.AgNPs exhibit their effectively inhibitory ability against A. niger, A. flavus and F. oxysporum as dose-dependence. Altogether, MC.AgNPs and PG.AgNPs will have much potential in scaled up production and become the promising fungicides for agricultural applications.

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Section: The Size and Morphology Of Mcagnps And Pgagnpsmentioning

confidence: 99%

Section: Antifungal Activity Of Mcagnps and Pgagnpsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Comparison of biogenic silver nanoparticles formed by Momordica charantia and Psidium guajava leaf extract and antifungal evaluation

Nguyen

et al. 2020

PLoS ONE

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“…The wide range of applications of metal nanoparticles have been extensively reported [8,9]. It had been demonstrated that silver nanoparticles/polymer composites exhibit enhanced antimicrobial activity [10][11][12][13], and hence can have application in medical treatments.…”

Section: Introductionmentioning

confidence: 99%

Preparation of Silver/Chitosan Nanofluids Using Selected Plant Extracts: Characterization and Antimicrobial Studies against Gram-Positive and Gram-Negative Bacteria

et al. 2020

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Chitosan/silver nanofluids were prepared using Phoenix dactylifera (DPLE) or Rumex vesicarius (HEL) extracts as the reducing agent, characterized using Fourier-transform infrared spectroscopy (FTIR), ultraviolet–visible (UV-vis), X-ray diffraction (XRD), and transmission electron microscope (TEM). The antimicrobial effect of the nanofluids against Gram positive, Bacillus licheniformis, Staphylococcus haemolyticus, Bacillus cereus, and Micrococcus luteus, and Gram-negative Pseudomonas aeruginosa, Pseudomonas citronellolis, and Escherichia coli bacteria has been studied. The nanoparticles were polydispersed in the chitosan matrix and are highly stable. The zeta potential of the silver nanoparticles in DPLE- and HEL-mediated composites is +46 mV and +56 mV, respectively. The FTIR results reveal that the free carboxylate groups in the plant biomaterial took part in stabilization process. HEL is a stronger reducing agent than DPLE and nanoparticles generated with HEL are smaller (8.0–36 nm) than those produced with DPLE (10–43 nm). DPLE- and HEL-mediated composites effectively inhibit the growth of the studied bacteria but HEL-mediated composite exhibited higher effect. The higher antimicrobial activity of HEL-mediated composite is linked to the smaller nanoparticles. The foregoing results indicate that HEL extract can be used in the green production of potential antimicrobial chitosan/silver nanofluids for biomedical and packaging applications.

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“…These natural polymers are highly advantageous owing to their cell proliferation and growth, tissue regeneration, non-toxicity, minimal inflammatory and immunological response induction characteristics. Additionally, their chemical structures provide unique physicochemical properties which are fundamental for skin regeneration processes [ 124 ].…”

Section: Wound Dressings In Skin Cancermentioning

confidence: 99%

Regenerative Wound Dressings for Skin Cancer

Pavel

Chircov

Rădulescu

et al. 2020

Cancers

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Skin cancer is considered the most prevalent cancer type globally, with a continuously increasing prevalence and mortality growth rate. Additionally, the high risk of recurrence makes skin cancer treatment among the most expensive of all cancers, with average costs estimated to double within 5 years. Although tumor excision is the most effective approach among the available strategies, surgical interventions could be disfiguring, requiring additional skin grafts for covering the defects. In this context, post-surgery management should involve the application of wound dressings for promoting skin regeneration and preventing tumor recurrence and microbial infections, which still represents a considerable clinical challenge. Therefore, this paper aims to provide an up-to-date overview regarding the current status of regenerative wound dressings for skin cancer therapy. Specifically, the recent discoveries in natural biocompounds as anti-cancer agents for skin cancer treatment and the most intensively studied biomaterials for bioactive wound dressing development will be described.

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Carbohydrate polymer-based silver nanocomposites: Recent progress in the antimicrobial wound dressings

Cited by 145 publications

References 178 publications

Comparison of biogenic silver nanoparticles formed by Momordica charantia and Psidium guajava leaf extract and antifungal evaluation

Comparison of biogenic silver nanoparticles formed by Momordica charantia and Psidium guajava leaf extract and antifungal evaluation

Preparation of Silver/Chitosan Nanofluids Using Selected Plant Extracts: Characterization and Antimicrobial Studies against Gram-Positive and Gram-Negative Bacteria

Regenerative Wound Dressings for Skin Cancer

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