Carbon-based electrochemical biosensors as diagnostic platforms for connected decentralized healthcare

Abstract

Electrochemical biosensors have the potential to provide rapid and inexpensive diagnostics while moving clinical testing from centralized labs to point-of-care (POC) applications. Conductive materials functionalized with bioreceptors that remain stable...

ClO-driven degradation of graphene oxide: new insights from DFT calculations

“…In this respect, in the last few years the enzymatic degradation of carbon nanostructures has been extensively analyzed in the literature. [1][2][3][4][5] This is mainly due to a large number of publications speculating about the possible uses of fullerenes, nanotubes, and graphene in biomedical applications, for example, as delivering therapeutic agents, 6 for the development of new diagnostic strategies, 7 tissue engineering, 8,9 biosensors, 10,11 and so on. Consequently, not only toxicity studies 12,13 but also efforts to develop strategies to achieve their complete elimination from the human body become crucial.…”

An overview of electrochemical biosensors used for COVID-19 detection

“…On the electrode surface, the bioreceptor is immobilized, becoming responsible for interacting with the specic target in a sample, where in the case of COVID-19, some of the main detection targets include virus-specic antigens, viral oligonucleotides and antibodies. 25,31,44,45 When the interaction between the bioreceptor and the target occurs, signal transduction is performed at the electrode to convert the interaction into a detectable electrical signal. This electrical signal occurs thanks to electrochemical reactions at the electrode/bioreceptor interface that are proportional to the concentration of the target present in the sample.…”

“…On the electrode surface, the bioreceptor is immobilized, becoming responsible for interacting with the specific target in a sample, where in the case of COVID-19, some of the main detection targets include virus-specific antigens, viral oligonucleotides and antibodies. 25,31,44,45…”

Comparative Analysis of the Hydrazine Interaction with Arylene Diimide Derivatives: Complementary Approach Using First Principles Calculation and Experimental Confirmation

“…1,2 Despite its widespread application, prolonged exposure to hydrazine poses a serious threat to the ecological environment and human well-being due to its neurotoxic, convulsant, and hepatotoxic nature. 3,4 Additionally, hydrazine exhibits the capability to form extended H-bonding arrays, resulting in extended molecular assemblies with diverse optical properties. 5,6 Nanostructured materials and nanomaterials are considered promising candidates for gas sensor design due to their large surface-to-volume ratio, numerous surface reactive sites, and tunable electronic/optical properties.…”

“…Hydrazine (N 2 H 4 ) stands out as a well-recognized industrial pnictogen hydride chemical, extensively utilized as both a propellant and a precursor to various agrochemicals, polymerization catalysts, and pharmaceutical drugs. , Despite its widespread application, prolonged exposure to hydrazine poses a serious threat to the ecological environment and human well-being due to its neurotoxic, convulsant, and hepatotoxic nature. , Additionally, hydrazine exhibits the capability to form extended H-bonding arrays, resulting in extended molecular assemblies with diverse optical properties. , …”