“…The reluctance to use CO 2 as an insufflation agent is likely due to both an insufficient awareness by endoscopists that room air is replaceable with CO 2 as well as the fact that many hospitals are not equipped with a CO 2 insufflator in the endoscopy suite [7,9]. Endoscopic CO 2 insufflators, such as CO 2 -efficient (E-Z-EM; Lake Success, NY) and the Olympus UCR (Olympus, Tokyo, Japan), are commercially available.…”