Carbon Dioxide Physiological Training at NASA

Law, Jennifer; Young, Millennia; Alexander, David; Mason, Sara S.; Wear, Mary L.; Méndez, C. M.; Stanley, David; Ryder, Valerie Meyers; Baalen, Mary Van

doi:10.3357/amhp.4552.2017

Cited by 13 publications

(11 citation statements)

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“…Therefore, neither device can simulate high-altitude training. The level of inhaled CO 2 in own research was lower compared with other research, in which gas mixtures containing >2% CO 2 in the inhaled air were used [ 6 , 32 ]. Thus, it would seem that inhaling air containing an average of 0.19% CO 2 would not lead to significant changes in work efficiency, acid–base balance, or current physiological responses of the body.…”

Section: Discussionmentioning

confidence: 57%

Acute Effects of Using Added Respiratory Dead Space Volume in a Cycling Sprint Interval Exercise Protocol: A Cross-Over Study

Danek

Michalik

Smolarek

et al. 2020

IJERPH

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Background: The aim of the study was to compare acute physiological, biochemical, and perceptual responses during sprint interval exercise (SIE) with breathing through a device increasing added respiratory dead space volume (ARDSV) and without the device. Methods: The study involved 11 healthy, physically active men (mean maximal oxygen uptake: 52.6 ± 8.2 mL∙kg1∙min−1). During four visits to a laboratory with a minimum interval of 72 h, they participated in (1) an incremental test on a cycle ergometer; (2) a familiarization session; (3) and (4) cross-over SIE sessions. SIE consisted of 6 × 10-s all-out bouts with 4-min active recovery. During one of the sessions the participants breathed through a 1200-mL ARDSv (SIEARDS). Results: The work performed was significantly higher by 4.4% during SIEARDS, with no differences in the fatigue index. The mean respiratory ventilation was significantly higher by 13.2%, and the mean oxygen uptake was higher by 31.3% during SIEARDS. Respiratory muscle strength did not change after the two SIE sessions. In SIEARDS, the mean pH turned out significantly lower (7.26 vs. 7.29), and the mean HCO3– concentration was higher by 7.6%. Average La− and rating of perceived exertion (RPE) did not differ between the sessions. Conclusions: Using ARDSV during SIE provokes respiratory acidosis, causes stronger acute physiological responses, and does not increase RPE.

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Section: Discussionmentioning

confidence: 57%

Acute Effects of Using Added Respiratory Dead Space Volume in a Cycling Sprint Interval Exercise Protocol: A Cross-Over Study

Danek

Michalik

Smolarek

et al. 2020

IJERPH

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“…The study concluded that there was a significant reduction in PaO2 from baseline and an increase in other respiratory adverse effects [16]. Another study conducted in a cohort of 130 astronauts subjected to high CO2 pressures during controlled training showed a significantly higher incidence of headache in the exposed group, in addition to respiratory symptoms and difficulty in concentrating [17]. At the University of Wollongong (Australia), a study on the effects of CO2 inhalation on workers wearing respiratory protection devices showed that high levels of carbon dioxide were associated with feelings of discomfort and significantly reduced tolerance and time of device use [18].…”

Section: Discussionmentioning

confidence: 99%

Mask-associated de novo headache in healthcare workers during the Covid-19 pandemic

Ramírez-Moreno

Ceberino

González-Plata³

et al. 2020

Preprint

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Introduction: The pandemic caused by the new coronavirus (COVID-19) has led to changes in the development of health care activities by health professionals. We analysed whether there is an association between the appearance of de novo headache according to the type of mask used, the related factors, as well as the impact of the headache on health professionals. Method: cross-sectional study in a tertiary hospital in Extremadura, Spain. We administered an online questionnaire to healthcare workers during the period of maximum incidence of COVID-19 in our setting. Results: n=306, 244 women (79.7%), with an average age of 43 years (range 23-65). Of the total, 129 (42.2%) were physicians, 112 (36.6%) nurses and 65 (21.2%) other health workers. 208 (79.7%) used surgical masks and 53 (20.3%) used filtering masks. Of all those surveyed, 158 (51.6%) presented de novo headache. The occurrence of headache was independently associated with the use of a filtering mask, OR 2.14 (IC95% 1.07-4.32), being a nurse OR 2.09 (IC95% 1.18-3.72) or another health worker OR 6.94 (IC95% 3.01-16.04) or having a history of asthma OR 0.29 (IC95% 0.09-0.89). Depending on the type of mask used there were differences in headache intensity. And the impact of headache in the subjects who used a filtering mask was worse in the all aspects evaluated. Conclusions: The appearance of de novo headache is associated with the use of filtering masks and is more frequent in certain health care workers, causing a greater occupational, family, personal and social impact.

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“…Symptoms of hypercapnia include lightheadedness, dizziness, and headaches, and can ultimately lead to collapse and death. 8,9 Mask protection classes comprise simple mouth-nose-protection (MNP) devices as well as filtering face piece (FFP) 1, 2 and 3 masks. FFP masks with and without expiration valves are currently in frequent use around the globe.…”

Section: Introductionmentioning

confidence: 99%

The use of personal protection equipment does not impair the quality of cardiopulmonary resuscitation

et al. 2021

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Aim: Prior studies suggest that the use of personal protective equipment might impair the quality of critical care. We investigated the influence of personal protective equipment on out-of-hospital cardiopulmonary resuscitation. Methods: Randomised controlled non-inferiority triple-crossover study. Forty-eight emergency medical service providers, randomized into teams of two, performed 12 min of basic life support (BLS) on a manikin after climbing 3 flights of stairs. Three scenarios were completed in a randomised order: Without personal protective equipment, with personal protective equipment including a filtering face piece (FFP) 2 mask with valve, and with personal protective equipment including an FFP2 mask without valve. The primary outcome was mean depth of chest compressions with a pre-defined non-inferiority margin of 3.5 mm. Secondary outcomes included other measurements of CPR quality, providers' subjective exhaustion levels, and providers' vital signs, including end-tidal CO 2. Results: Differences regarding the primary outcome were well below the pre-defined non-inferiority margins for both control vs. personal protective equipment without valve (absolute difference 1 mm, 95% CI [À1, 2]) and control vs. personal protective equipment with valve (absolute difference 1 mm, [À0.2, 2]). This was also true for secondary outcomes regarding quality of chest compressions and providers' vital signs including etCO 2. Subjective physical strain after BLS was higher in the personal protective equipment groups (Borg 4 (SD 3) without valve, 4 (SD 2) with valve) than in the control group (Borg 3 (SD 2)). Conclusion: PPE including masks with and without expiration valve is safe for use without concerns regarding the impairment of CPR quality.

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Carbon Dioxide Physiological Training at NASA

Cited by 13 publications

References 0 publications

Acute Effects of Using Added Respiratory Dead Space Volume in a Cycling Sprint Interval Exercise Protocol: A Cross-Over Study

Acute Effects of Using Added Respiratory Dead Space Volume in a Cycling Sprint Interval Exercise Protocol: A Cross-Over Study

Mask-associated de novo headache in healthcare workers during the Covid-19 pandemic

The use of personal protection equipment does not impair the quality of cardiopulmonary resuscitation

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