Carbon dots with red-shifted photoluminescence by fluorine doping for optical bio-imaging

Yang, Wanning; Zhang, Hong; Lai, Junxin; Peng, Xiujuan; Hu, Yuan; Gu, Wei; Ye, Ling

doi:10.1016/j.carbon.2017.11.069

Cited by 165 publications

(73 citation statements)

References 38 publications

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“…Recently, Yang et al developed citrate-based CDs with red-shifted fluorescence under excitation at 530 nm through fluorine doping. [40] The obtained red-emissive fluorine doped CDs were later applied for both in vitro cell imaging and in vivo tumor imaging, demonstrating promising bioimaging potential for theranostic applications.…”

Section: Citrate-based Carbon Dots (Cds)mentioning

confidence: 99%

Citrate‐Based Fluorescent Biomaterials

Shan

Hsieh

Bai

et al. 2018

Adv Healthcare Materials

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Fluorescence imaging has emerged as a promising technique for monitoring and assessing various biologically relevant species in cells and organisms, driving the demand for effective fluorescent agents with good biocompatibility and high fluorescence performance. However, traditional fluorescent agents, such as quantum dots (QDs) and organic dyes, either suffer from toxicity concerns or poor fluorescence performance (e.g., low photobleaching-resistance). In this regard, citrate-based fluorescent biomaterials, which are synthesized from the natural and biocompatible precursor of citric acid (CA), have become competitive alternatives for fluorescence imaging owing to their biocompatibility, cost effectiveness, straightforward synthetic routes, flexible designability, as well as strong fluorescence with adjustable excitation/emission wavelengths. Accordingly, numerous citrate-based biomaterials, including carbon dots (CDs), biodegradable photoluminescent polymers (BPLPs), and small molecular fluorophores, have been developed and researched in the past few decades. This review discusses recent progress in the research and development of citrate-based fluorescent materials with emphasis on their design and synthesis considerations, material properties, fluorescence properties and mechanisms, as well as biomedical applications. It is expected that this review will provide an insightful discussion on the citrate-based fluorescent biomaterials, and lead to innovations for the next generation of fluorescent biomaterials and fluorescence-based biomedical technology.

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Section: Citrate-based Carbon Dots (Cds)mentioning

confidence: 99%

Citrate‐Based Fluorescent Biomaterials

Shan

Hsieh

Bai

et al. 2018

Adv Healthcare Materials

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“…CDs with oxygen‐containing functional groups (OH, COOH, etc.) are easy to realize surface functionalization with so that they possess certain chemical characteristics . CDs have usually been used to improve the water retention capacity of composite membranes .…”

Section: Introductionmentioning

confidence: 99%

Effect of carbon dots with chitosan coating on microorganisms and storage quality of modified‐atmosphere‐packaged fresh‐cut cucumber

et al. 2019

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BACKGROUND In order to inhibit microorganisms and improve storage quality of fresh‐cut cucumber, fresh‐cut cucumber was treated by carbon dots (CDs) from kelp/chitosan (CH) coating solution with CD concentrations of 0%, 1.5%, 3% and 4.5% and then packaged as well as stored at 4 °C for 15 days. The effect of CDs/CH coating on microorganisms and the quality of modified‐atmosphere‐packaged fresh‐cut cucumber during storage were investigated. RESULTS The CDs was monodispersed spherical morphology with size distribution of 0.54–0.83 nm. Interaction of CDs and CH had the generation of strong hydrogen bond. Inhibition zone diameters of CDs/CH coating against Staphylococcus aureus and Escherichia coli were enhanced with the increase of CD concentrations. Moreover, CDs/CH coating inhibited the growth of total number of colonies, mold, and yeast in modified‐atmosphere‐packaged fresh‐cut cucumber during storage. A coating of 4.5% CDs/CH effectively reduced the losses of weight, firmness, and total soluble solids, the degradation of ascorbic acid content and flavor, and inhibited peroxidases activity, as well as decreased water mobility in fresh‐cut cucumber during storage. CONCLUSION The results indicated that a CDs/CH coating was helpful for inhibiting microorganisms and improving storage quality, and could be an effective method to prolong shelf life of fresh‐cut cucumber. © 2019 Society of Chemical Industry

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“…CDs are formed by small carbon molecules that are surface-passivated by organic molecules or biomolecules becoming strongly fluorescent in the visible and near-infrared (NIR) spectral regions. Several research groups have carried out studies using CDs to produce OI in vivo [133,134].…”

Section: Quantum Dotsmentioning

confidence: 99%

Molecular Imaging with 68Ga Radio-Nanomaterials: Shedding Light on Nanoparticles

et al. 2018

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Abstract:The combination of radioisotopes and nanomaterials is creating a new library of tracers for molecular imaging, exploiting the sensitivity of nuclear imaging techniques and the size-dependent properties of nanomaterials. This new approach is expanding the range of applications, including the possibility of theranostics. Among the many different combinations, the use of 68 Ga as the radioisotope in the radio-nanomaterial is particularly convenient. The physicochemical properties of this isotope allow incorporating it into many materials with great chemical flexibility. Furthermore, its production from a benchtop generator eases the preparation of the tracer. Here, we review main results from the last years in which a nanomaterial has been radiolabeled with 68 Ga. In thus process, we pay attention to the use of nanomaterials for biomedical imaging in general and main properties of this radioisotope. We study the main methods to carry out such radiolabeling and the most important applications for molecular imaging.

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Carbon dots with red-shifted photoluminescence by fluorine doping for optical bio-imaging

Cited by 165 publications

References 38 publications

Citrate‐Based Fluorescent Biomaterials

Citrate‐Based Fluorescent Biomaterials

Effect of carbon dots with chitosan coating on microorganisms and storage quality of modified‐atmosphere‐packaged fresh‐cut cucumber

Molecular Imaging with 68Ga Radio-Nanomaterials: Shedding Light on Nanoparticles

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