Carbon microspheres uniformly decorated with ceria nanoparticles as an ultrasensitive platform for electrochemical sensing of antihypertensive drug lacidipine in patient plasma and pharmaceutical formulation

Nanosensors in the detection of antihypertension drugs, a golden step for medication adherence monitoring

“…A novel ultrasensitive lacidipine (LCDP) electrochemical biosensor was created based on functionalized glassy carbon (FGC) microspheres anchored with ceria nanoparticles (CeO 2 NPs@FGC, ratio 2:1 w/w). Furthermore, the invented sensor displays favorable reproducibility, acceptable selectivity, and long-term stability [ 52 ].…”

Surface engineering of carbon microspheres with nanoceria wrapped on MWCNTs: a dual electrocatalyst for simultaneous monitoring of molnupiravir and paracetamol

“…Many methods are described in the literature that can measure MPV or PCM using HPLC, [12][13][14] UV spectrophotometry, 15,16 and electrochemical methods. [17][18][19][20][21][22][23][24][25][26][27][28] However, except for electrochemical methods, all other analytical methods are complicated, tedious, timeconsuming, and expensive. Electrochemical methods are timesaving, simple, real-time, user-friendly, and economically worthwhile.…”

“…A huge variety of materials, such as metal oxide nanoparticles and carbon-based composites, are available. [29][30][31][32] In recent years, nanoparticlebased metal oxide electrochemical sensors have garnered a great deal of interest in electrocatalysis. [33][34][35] Due to its unique properties, nano-CeO 2 (CeNPs) has been applied in various elds, including supercapacitors, solar cells, photocatalysis, and sensors.…”

“…Among the family of carbon, glassy carbon microspheres (GCMs) are the most popular electrode material, offering attractive electrochemical reactivity, negligible porosity, and good mechanical rigidity. 29,34 Glassy carbon paste electrodes (GCPEs) combine the attractive properties of composite electrodes and glassy carbon because the preparation of these electrodes includes the mixing of GCMs with organic-pasting liquid. GCPEs offer high electrochemical reactivity, a wide accessible potential window; low background current; are easy to prepare, modify, and renew; and are inexpensive.…”