Carbon Monoxide Poisoning

Kao, Louise; Nañagas, Kristine

doi:10.1016/j.mcna.2005.06.007

Cited by 93 publications

(102 citation statements)

References 209 publications

(324 reference statements)

Supporting

Mentioning

101

Contrasting

Unclassified

Order By: Relevance

“…1 Exposure to CO can be extremely harmful to human health with the early effects of poisoning often going unnoticed. The early symptoms of acute CO poisoning include headache, dizziness, weakness, nausea, confusion, disorientation, and visual disturbances, 2 which can be easily confused with general ill-health.…”

Section: Introductionmentioning

confidence: 99%

Unintentional carbon monoxide poisoning in Northwest Iran: A 5-year study

Nazari

Dianat

Stedmon

2010

Journal of Forensic and Legal Medicine

View full text Add to dashboard Cite

Section: Introductionmentioning

confidence: 99%

Unintentional carbon monoxide poisoning in Northwest Iran: A 5-year study

Nazari

Dianat

Stedmon

2010

Journal of Forensic and Legal Medicine

View full text Add to dashboard Cite

“…Carbon monoxide poisoning is the leading cause of injury and death in the world [1]. The clinical symptoms of CO poisoning are often nonspecific and diverse, and not confined to immediate responses.…”

Section: Introductionmentioning

confidence: 99%

Lipid Peroxidation was Involved in the Memory Impairment of Carbon Monoxide-induced Delayed Neuron Damage

et al. 2009

View full text Add to dashboard Cite

Carbon monoxide (CO)-induced delayed neuron damage is the serious complication, but the underlying mechanisms are poorly understood. This study was designed to investigate the time-dependent changes of the lipid peroxidation (malondialdehyde, MDA) and antioxidative status (glutathione, GSH; glutathione peroxidase, GSH-Px; glutathione reductase, GR; and anti-reactive oxygen species anti-ROS) in nerve tissues for the possible mechanisms exploration. Adult rats were treated with CO by peritoneal injection, and sacrificed after day 0, 1, 3, 7, 14 and 21 of treatment. The results showed that the step-down latency progressively shortened while the numbers of error increased. Comparing with the level of day 0, MDA levels in serum, cerebral cortex and hippocampus significantly increased on day 1, 3 and 7. The level of GSH increased firstly but then decreased. The activities of GR, GSH-Px, and anti-ROS decreased in serum, cerebral cortex and hippocampus of rats after day 1, 3, 7, 14 and 21. Thus, we concluded that CO-mediated delayed neuron damage might be associated with elevation of lipid peroxidation and reduction of antioxidative status. The time-dependent changes of lipid peroxidation and antioxidative status in serum, cerebral cortex and hippocampus, at least in part, are involved in the toxic effects of CO poisoning on neuron.

show abstract

“…This indirectly indicates towards the presence of a significant level of CO in the blood in the bound form as COHb. A number of studies (Jarvis 1986;Kao and Nanagas, 2005;Thompson et al, 2011) have reported a strong relationship between blood CO levels (i.e., %COHb) and exhaled breath CO.…”

Section: Variations Of Co Concentration During the Cooking Cyclementioning

confidence: 99%

“…This results in a decrease in the amount of oxygen in blood, thus causing tissue hypoxia (Roughton, 1944;Piantadosi, 1996). Health effects from acute exposures to CO include headache, dizziness, muscular cramping, vomiting, unconsciousness and death (Penney, 1996;Kao and Nanagas, 2005). Chronic exposure to levels as low as 2.5% of COHb are associated with an increased risk of ischemic heart disease (WHO, 2010).…”

Section: Introductionmentioning

confidence: 99%

“…Chronic exposure to levels as low as 2.5% of COHb are associated with an increased risk of ischemic heart disease (WHO, 2010). Measuring COHb concentration from venous or arterial blood is considered the standard and most direct method for measuring CO body burden (Widdop, 2002;Kao and Nanagas, 2005). Even though COHb is a biological indicator of the concentration of CO in the body, measuring COHb levels is not always possible due to the invasive nature of collecting blood samples.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Non-Invasive Measurement of Carbon Monoxide in Rural Indian Woman Exposed to Different Cooking Fuel Smoke

Joon

Kumar

Bhattacharya

et al. 2014

Aerosol Air Qual. Res.

View full text Add to dashboard Cite

In India more than 70% of the population use biomass fuels for cooking. Women, who traditionally carry out the cooking in this culture, experience the highest lifetime Carbon Monoxide (CO) exposure due to the burning of such fuels in traditional stoves. CO levels were measured in this study in the breathing zone atmosphere of cooks during the cooking cycle, using different fuels such as LPG, wood, crop residues and dung cakes, in a rural area of the National Capital Region (NCR) of India. The exhaled breath CO levels of the non-smoking female cooks were also measured before and after cooking. A high degree of correlation was obtained between CO levels during the cooking cycle and exhaled breath CO levels. The study suggests that the enhanced exhaled breath CO levels of the cooks were largely due to the burning of biomass fuels. A high value of R 2 (0.79) was obtained during the model fitting exercise, which suggests the usefulness of fuel-type and cooking location (i.e., indoor/outdoor) as explanatory variables for predicting exhaled breath CO levels among cooks. The prevalence of CO poisoning symptoms was found to be significantly higher among the biomass fuel users. The study demonstrates the potential of the exhaled breath CO technique as a non-invasive, easy and economical alternative for predicting CO exposure due to the burning of biomass fuel in rural settings, where it may not always be possible to collect CO exposure data using the conventional invasive techniques.

show abstract

Carbon Monoxide Poisoning

Cited by 93 publications

References 209 publications

Unintentional carbon monoxide poisoning in Northwest Iran: A 5-year study

Unintentional carbon monoxide poisoning in Northwest Iran: A 5-year study

Lipid Peroxidation was Involved in the Memory Impairment of Carbon Monoxide-induced Delayed Neuron Damage

Non-Invasive Measurement of Carbon Monoxide in Rural Indian Woman Exposed to Different Cooking Fuel Smoke

Contact Info

Product

Resources

About