Carbon monoxide poisoning in Iran during 1999–2016: A systematic review and meta-analysis

Hosseininejad, Seyed Mohammad; Aminiahidashti, Hamed; Khatir, Iraj Goli; Ghasempouri, Seyed Khosro; Jabbari, Ali; Khandashpour, Mahmoud

doi:10.1016/j.jflm.2017.11.008

Cited by 25 publications

(22 citation statements)

References 21 publications

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“…Some studies in Iran have also shown that about 10% of poisonings in Iran are due to CO and reported mortality rate 3.1 per 100,000 population in 2016 (9). Another study showed that the mortality ratio of this poisoning was 11.6 per 1000 deaths in 2016 (10).…”

Section: Introductionmentioning

confidence: 98%

Deaths from Carbon monoxide poisoning in Iran between 2011 and 2018- An ecological study

Alimohamadi¹,

Rahimi²,

Mehri³

2020

Preprint

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Background: Carbon monoxide (CO) poisoning, as one of the lethal poisoning, is responsible for a large percentage of poisonings and accidental deaths. Since the investigation of the mortality and the distribution of CO poisoning deaths in Iranian provinces is still unknown and no study has investigated so far, this study was conducted to determine the trend of mortality rate changes due to CO poisoning by Spatio-temporal analysis in Iran from 2011 to 2018. Methods: An ecological study was conducted based on data from the reports of at the National Center for Statistics of Iran for eight years from 21 March 2011 to 21 March 2018. The number of deaths due to CO poisoning and the annual mortality rates of CO poisoning per 100,000 population were calculated. The Spatio-temporal analysis used to determine the spatial and temporal distribution of deaths.Results: A total of 6078 deaths were reported due to CO poisoning that 4497 death were male (74%) and 1596 were female (26%) from 2011 to 2018. In both sexes, the mortality rate due to CO poisoning was 1.26 from 2011 to 0.91 in 2018. According to the results, the overall male-to-female ratio was 2.8. The mortality rate due to CO Poisoning had a decreasing trend. However, this trend did not have a linear trend (p=0.37). Our results showed that most of the deaths due to CO poisoning are higher in the northern and western provinces of Iran.Conclusion: This study is one of the first studies to compare the spatial and temporal mortality rates due to CO poisoning in Iran. Paying attention to general education about the principles of safety in the installation of heaters and the use of the gas networks, continuous and accurate monitoring of the installation and operation of CO-producing, and the use of sensitive alarms can reduce mortality and morbidity due to CO poisoning.

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Section: Introductionmentioning

confidence: 98%

Deaths from Carbon monoxide poisoning in Iran between 2011 and 2018- An ecological study

Alimohamadi¹,

Rahimi²,

Mehri³

2020

Preprint

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“…Its effectiveness for preventing DNS is not clear, and there are uncertainties surrounding the optimum HBOT protocol. 5 , 9 , 13 , 14 Studies reporting increased fractional anisotropy after HBOT are consistent with the reversal of myelin damage by HBOT. 15 Other experimental treatments have been evaluated in clinical trials, including anti-inflammatory and immunomodulatory agents such as immuneglobulin, interferon, glatiramer acetate, and steroids, but with limited success.…”

Section: Discussionmentioning

confidence: 55%

“… 12 Hydrogen-rich saline has a lower hydroxyl radical concentration than water, has low toxicity, and is thought to be neuroprotective in ischemia-reperfusion injury. 14 Allopurinol reportedly protects against brain ischemia and oxidative-stress-induced reperfusion injury; it also decreases the severity of DNS by inhibiting xanthine oxidoreductase, which promotes free radical production during cerebral ischemia/reperfusion. 5 CO toxicity stimulates oxidative stress in the brain, with protective responses including the accumulation of superoxide dismutase (SOD-1, SOD-2), HO-1, nitric oxide synthase, and nitrotyrosine.…”

Section: Discussionmentioning

confidence: 99%

Delayed neurologic sequelae of carbon monoxide intoxication

Sönmez

İşcanlı

Parlak

et al. 2018

Turkish Journal of Emergency Medicine

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Altered consciousness and accompanying neurological symptoms are both complex and challenging cases for emergency physicians. These are not specific and may be a sign of a variety of medical conditions including stroke and delayed neurological sequelae (DNS) is a recurrent transient neuropsychiatric consequence of CO intoxication. DNS produces a spectrum of varying symptoms and the diagnosis is primarily made on the basis of clinical features and radiological findings from CT and conventional MRI. In clinical practice, serious CO intoxication is treated only with oxygen therapy although no effective treatment exists. Emergency physicians play a major role in managing patients presenting with CO intoxication and preventing DNS.

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“…Some studies in Iran have shown that about 10% of poisonings in Iran are due to CO and reported mortality rate 3.1 per 100,000 population in 2016 (8). Another study showed that the mortality ratio of this poisoning was 11.6 per 1000 deaths in 2016 (9).…”

Section: Introductionmentioning

confidence: 99%

Spatio-temporal analysis of Deaths from carbon monoxide poisoning in Iran between 2011 and 2018- An ecological study

Alimohamadi

Rahimi

Mehri

2020

Preprint

View full text Add to dashboard Cite

Background Carbon monoxide (CO) poisoning, as one of the lethal poisoning, is responsible for a large percentage of poisonings and accidental deaths. Since the investigation of the mortality and the distribution of CO poisoning deaths in Iranian provinces is still unknown and no study has investigated so far, this study was conducted to determine the trend of mortality rate changes due to CO poisoning by Spatio-temporal analysis in Iran from 2011 to 2018. Methods An ecological study was conducted based on data from the reports of at the National Center for Statistics of Iran for eight years from 21 March 2011 to 21 March 2018. The number of deaths due to CO poisoning and the annual mortality rates of CO poisoning per 100,000 population were calculated. The Spatio-temporal analysis used to determine the spatial and temporal distribution of deaths. Results A total of 6078 deaths were reported due to CO poisoning that 4497 death were male (74%) and 1596 were female (26%) from 2011 to 2018. In both sexes, the mortality rate due to CO poisoning was 1.26 from 2011 to 0.91 in 2018. According to the results, the overall male-to-female ratio was 2.8. The mortality rate due to CO Poisoning had a decreasing trend. However, this trend did not have a linear trend (p=0.37). Our results showed that most of the deaths due to CO poisoning are higher in the northern and western provinces of Iran. Conclusion This study is one of the first studies to compare the spatial and temporal mortality rates due to CO poisoning in Iran. Paying attention to general education about the principles of safety in the installation of heaters and the use of the gas networks, continuous and accurate monitoring of the installation and operation of CO-producing, and the use of sensitive alarms can reduce mortality and morbidity due to CO poisoning.

show abstract

Carbon monoxide poisoning in Iran during 1999–2016: A systematic review and meta-analysis

Cited by 25 publications

References 21 publications

Deaths from Carbon monoxide poisoning in Iran between 2011 and 2018- An ecological study

Deaths from Carbon monoxide poisoning in Iran between 2011 and 2018- An ecological study

Delayed neurologic sequelae of carbon monoxide intoxication

Spatio-temporal analysis of Deaths from carbon monoxide poisoning in Iran between 2011 and 2018- An ecological study

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