Carbon Nanotube-Based Antimicrobial and Antifouling Surfaces

Teixeira‐Santos, Rita; Gomes, Marisa; Mergulhão, Filipe

doi:10.1007/978-981-15-4630-3_4

Cited by 7 publications

(12 citation statements)

References 86 publications

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“…Described as sheets of graphene rolled up into cylinders (with several micrometres in length and nanometres in diameter), they can be classified as single-(SWCNTs) and multi-walled CNTs (MWCNTs), accordingly to the number of graphene layers [19,20]. Because of their outstanding properties, such as electrical conductivity, high aspect ratio and mechanical strength, flexibility, high surface energy density, chemical stability, and the possibility of functionalization with a wide variety of moieties (antimicrobial drugs and other bioactive molecules), CNT-based surfaces have been widely applied in the medical field, and in particular for the manufacture of medical devices [18,21]. Although there is still little consensus regarding the mechanisms behind the CNTs' antimicrobial activity, different influencing factors have been described, including CNT diameter and length, purity, electronic structure, CNT aggregation and surface functional groups, as well as CNT type (SWCNT or MWCNT) [22].…”

Section: Introductionmentioning

confidence: 99%

“…Despite the proven antimicrobial activity of CNT composites [18,21], their application as a coating for urinary tract devices is still unexplored and supplementary investigations are required to improve their antimicrobial properties. To the best of our knowledge, only two studies have been devoted to the development of antimicrobial CNT composites for application in urinary tract devices in controlled hydrodynamic conditions [23,24].…”

Section: Introductionmentioning

confidence: 99%

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Optimizing CNT Loading in Antimicrobial Composites for Urinary Tract Application

Gomes

Teixeira‐Santos

et al. 2021

Applied Sciences

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Several methodologies have been implemented with the intent of preventing or reducing the formation of biofilms on indwelling urinary devices. The use of carbon nanotubes (CNTs) in the biomedical field has been increasing, particularly in the production of antimicrobial and antifouling coatings. Despite their proven antimicrobial properties, their use as coating materials for urinary tract devices (UTDs) is still poorly documented. In the present work, CNT/poly(dimethylsiloxane) (PDMS) composite materials containing different CNT loadings were prepared and further tested against Escherichia coli under conditions prevailing in UTDs. Besides CNT loading optimization, textural modifications were also introduced on the surface of CNTs to improve the antibiofilm pro-perties of the final composites. Material characterization included the textural evaluation of CNTs and the assessment of surface morphology by scanning electron microscopy, while the surface hydrophobicity was determined by contact angle measurements. Biofilm analysis was performed by determining the number of culturable and total cells and by confocal laser scanning microscopy. Results revealed that, by filling the PDMS matrix with 3 wt% CNT loading, a significant reduction in cell culturability (39%) can be achieved compared to PDMS. Additionally, the textural modifications induced by ball-milling treatment proved to be effective on the inhibition of biofilm formation, reducing the amount of biofilm per surface area, biofilm thickness and surface coverage in 31, 47 and 27%, respectively (compared to surfaces where CNTs were not ball-milled).

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Optimizing CNT Loading in Antimicrobial Composites for Urinary Tract Application

Gomes

Teixeira‐Santos

et al. 2021

Applied Sciences

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“…104 The antibacterial activity of CNTs mainly depends on the number of graphene layers, aspect ratio, and physical disposition. 154 Previous studies demonstrated the effectiveness of MWCNTs nanocomposites in the removal of bacterial adhesion and biofilm. 46,89 For instance, poly(dimethylsiloxane) (PDMS) is widely used in the production of implants and medical devices in the biomedical industry.…”

Section: Application Of Cnts In Urinary Tract Devicesmentioning

confidence: 99%

An Overview of Antimicrobial Properties of Carbon Nanotubes-Based Nanocomposites

et al. 2021

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The development of carbon-based nanomaterials has extensively facilitated new discoveries in various fields. Carbon nanotube-based nanocomposites (CNT-based nanocomposites) have lately recognized as promising biomaterials for a wide range of biomedical applications due to their unique electronic, mechanical, and biological properties. Nanocomposite materials such as silver nanoparticles, polymers, biomolecules, enzymes, and peptides have been reported in many studies, possess a broad range of antibacterial activity when incorporated with carbon nanotubes (CNTs). It is crucial to understand the mechanism which governs the antimicrobial activity of these CNT-based nanocomposite materials, including the decoupling individual and synergistic effects on the cells. In this review, the interaction behavior between microorganisms and different types of CNT-based nanocomposites is summarized to understand the respective antimicrobial performance in different conditions. Besides, the current development stage of CNT-based nanocomposite materials, the technical challenges faced, and the exceptional prospect of implementing potential antimicrobial CNT-based nanocomposite materials are also discussed.

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“…The high swelling ability and fragile nature of alginate polymer make the poor moisture barrier of packaging films [17,18]. The unprecedented opportunities in the field of nanotechnology open the unique way for natural polymers to withstand versatile industrial conditions and show multidimensional functions [19,20]. In this way, natural polymers are reinforced with nanomaterials to modify the potential properties uniquely.…”

Section: Introductionmentioning

confidence: 99%

Synthesis of alginate-based antibacterial and antioxidant food packaging films

Bibi

Rehman

Akhtar

2022

Environmental Engineering Research

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This study contributes to the preliminary development of the active food packaging materials by using bio-based polymers under ultrasonic waves. For this alginate (Algi) polymer was reinforced with functionalized multiwalled carbon nanotubes (COOH-MWCNTs) dispersed in surfactants to form A-type of films. Similarly, to form a B-type of films, Algi polymer was blended with polyvinyl alcohol (PVA) in the presence of COOH-MWCNTs. The synthesized films were physiochemically characterized by FTIR, SEM, TEM, and mechanical testing. The antibacterial and antioxidant properties of prepared films were assessed by agar well diffusion method and ABTS/Ferrozine methods, respectively. Synthesized films showed prominent peaks of Algi, PVA, and of COOH-MWCNTs in FTIR analysis and dispersed nanofillers in SEM/TEM study. The Youngs Modulus of AD90 is 249.17 N/mm2, Bs90 is 216.80 N/mm2 and of Algi is 129.55 N/mm2. Staphylococcus aureus is the positive and Klebsiella pneumonia, Escherichia coli are the negative strains of bacteria that were successfully inhibited to grow by the prepared films. Synthesized materials also acted as strong antioxidants with no significant difference (P > 0.05) from ascorbic acid compared to Algi tested by ABTS and Ferrozine methods.

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Carbon Nanotube-Based Antimicrobial and Antifouling Surfaces

Cited by 7 publications

References 86 publications

Optimizing CNT Loading in Antimicrobial Composites for Urinary Tract Application

Optimizing CNT Loading in Antimicrobial Composites for Urinary Tract Application

An Overview of Antimicrobial Properties of Carbon Nanotubes-Based Nanocomposites

Synthesis of alginate-based antibacterial and antioxidant food packaging films

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