Carbon Nanotubes: A Summary of Beneficial and Dangerous Aspects of an Increasingly Popular Group of Nanomaterials

Zhang, Chengke; Wu, Licun; Perrot, Marc de; Zhao, Xiaogang

doi:10.3389/fonc.2021.693814

Cited by 32 publications

(20 citation statements)

References 119 publications

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“…These nanomaterials are characterized by interesting mechanical (high tensile strength and Young’s modulus), electric, and thermal properties [ 41 ]. There are many methods for obtaining CNTs, which include chemical vapor deposition (CVD), laser ablation, and arc-discharge deposition [ 42 ]. It has been proven that the properties of nanotubes are affected by the degree of their ordering; the lower the ordering, the greater the deterioration of the mechanical and electrical properties.…”

Section: Classification and Basic Properties Of Carbon Nanomaterialsmentioning

confidence: 99%

Modern Electrochemical Biosensing Based on Nucleic Acids and Carbon Nanomaterials

Szymczyk

Ziółkowski

Malinowska

2023

Sensors

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To meet the requirements of novel therapies, effective treatments should be supported by diagnostic tools characterized by appropriate analytical and working parameters. These are, in particular, fast and reliable responses that are proportional to analyte concentration, with low detection limits, high selectivity, cost-efficient construction, and portability, allowing for the development of point-of-care devices. Biosensors using nucleic acids as receptors has turned out to be an effective approach for meeting the abovementioned requirements. Careful design of the receptor layers will allow them to obtain DNA biosensors that are dedicated to almost any analyte, including ions, low and high molecular weight compounds, nucleic acids, proteins, and even whole cells. The impulse for the application of carbon nanomaterials in electrochemical DNA biosensors is rooted in the possibility to further influence their analytical parameters and adjust them to the chosen analysis. Such nanomaterials enable the lowering of the detection limit, the extension of the biosensor linear response, or the increase in selectivity. This is possible thanks to their high conductivity, large surface-to-area ratio, ease of chemical modification, and introduction of other nanomaterials, such as nanoparticles, into the carbon structures. This review discusses the recent advances on the design and application of carbon nanomaterials in electrochemical DNA biosensors that are dedicated especially to modern medical diagnostics.

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Section: Classification and Basic Properties Of Carbon Nanomaterialsmentioning

confidence: 99%

Modern Electrochemical Biosensing Based on Nucleic Acids and Carbon Nanomaterials

Szymczyk

Ziółkowski

Malinowska

2023

Sensors

View full text Add to dashboard Cite

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“…Carbon nanotubes are hollow nanosized cylindrical tubes composed of graphite sheets (graphene). Nanotubes are classified as either single- or multi-walled depending on the number of layers [ 109 , 110 ]. Studies of single- and multi-walled carbon nanotube (SWCNTs and MWCNTs, respectively) toxicity have shown deleterious effects in cells, mammals, aquatic organisms, and plants.…”

Section: Factors Affecting Toxicitymentioning

confidence: 99%

Potential Environmental and Health Implications from the Scaled-Up Production and Disposal of Nanomaterials Used in Biosensors

et al. 2022

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Biosensors often combine biological recognition elements with nanomaterials of varying compositions and dimensions to facilitate or enhance the operating mechanism of the device. While incorporating nanomaterials is beneficial to developing high-performance biosensors, at the stages of scale-up and disposal, it may lead to the unmanaged release of toxic nanomaterials. Here we attempt to foster connections between the domains of biosensors development and human and environmental toxicology to encourage a holistic approach to the development and scale-up of biosensors. We begin by exploring the toxicity of nanomaterials commonly used in biosensor design. From our analysis, we introduce five factors with a role in nanotoxicity that should be considered at the biosensor development stages to better manage toxicity. Finally, we contextualize the discussion by presenting the relevant stages and routes of exposure in the biosensor life cycle. Our review found little consensus on how the factors presented govern nanomaterial toxicity, especially in composite and alloyed nanomaterials. To bridge the current gap in understanding and mitigate the risks of uncontrolled nanomaterial release, we advocate for greater collaboration through a precautionary One Health approach to future development and a movement towards a circular approach to biosensor use and disposal.

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“…One of the key benefits of this approach is that covalent bonding between the functionalized carbon nanotubes and the polymer matrix is possible, resulting in significantly developed mechanical characteristics of composites via strong interfacial bonds. This process frequently achieves greater filler dispersion than melt mixing, and in the case of in situ polymerization, it is possible to separate aggregated nanotubes with little energy input using a low viscosity solvent such as toluene as a pretreatment solvent [26]. Heavy metal adsorption is demonstrated using functionalized derivatives of carbon nanotubes and graphene with large surface areas and adsorption sites, addressing the pressing heavy metal pollution problem.…”

Section: Review Of the Carbon Nanotube Constructionmentioning

confidence: 99%

Recent Insights and Multifactorial Applications of Carbon Nanotubes

et al. 2021

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Nanotechnology has undergone significant development in recent years, particularly in the fabrication of sensors with a wide range of applications. The backbone of nanotechnology is nanostructures, which are determined on a nanoscale. Nanoparticles are abundant throughout the universe and are thought to be essential building components in the process of planet creation. Nanotechnology is generally concerned with structures that are between 1 and 100 nm in at least one dimension and involves the production of materials or electronics that are that small. Carbon nanotubes (CNTs) are carbon-based nanomaterials that have the structure of tubes. Carbon nanotubes are often referred to as the kings of nanomaterials. The diameter of carbon is determined in nanometers. They are formed from graphite sheets and are available in a variety of colors. Carbon nanotubes have a number of characteristics, including high flexibility, good thermal conductivity, low density, and chemical stability. Carbon nanotubes have played an important part in nanotechnology, semiconductors, optical and other branches of materials engineering owing to their remarkable features. Several of the applications addressed in this review have already been developed and used to benefit people worldwide. CNTs have been discussed in several domains, including industry, construction, adsorption, sensors, silicon chips, water purifiers, and biomedical uses, to show many treatments such as injecting CNTs into kidney cancers in rats, drug delivery, and directing a near-infrared laser at the cancers. With the orderly development of research in this field, additional therapeutic modalities will be identified, mainly for dispersion and densification techniques and targeted drug delivery systems for managing and curing posterior cortical atrophy. This review discusses the characteristics of carbon nanotubes as well as therapeutic applications such as medical diagnostics and drug delivery.

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Carbon Nanotubes: A Summary of Beneficial and Dangerous Aspects of an Increasingly Popular Group of Nanomaterials

Cited by 32 publications

References 119 publications

Modern Electrochemical Biosensing Based on Nucleic Acids and Carbon Nanomaterials

Modern Electrochemical Biosensing Based on Nucleic Acids and Carbon Nanomaterials

Potential Environmental and Health Implications from the Scaled-Up Production and Disposal of Nanomaterials Used in Biosensors

Recent Insights and Multifactorial Applications of Carbon Nanotubes

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