Abstract:Biocompatible nanomaterials have attracted enormous interest for biomedical applications. Carbonaceous materials, including carbon nanotubes (CNTs), have been widely explored in wound healing and other applications because of their superior physicochemical and potential biomedical properties to the nanoscale level. CNTs-based hydrogels are widely used for wound-healing and antibacterial applications. CNTs-based materials exhibited improved antimicrobial, antibacterial, adhesive, antioxidants, and mechanical pr… Show more
“… Fig. 1 Schematic structure of defect-free (a) SWCNT, (b) DWCNT, (c) MWCNT (reprinted from reference 21 , under the terms of the Creative Commons CC BY license). …”
Electronic products are becoming an essential part of our daily life. There is a huge demand to produce small and portable but powerful electronic products. Carbon nanotubes (CNTs) have excellent electrical, mechanical and thermal properties which can be exploited to build next-generation electronics. This paper reviews different types and properties of CNTs and also presents the CNT-based electronics along with their advantage over the conventionally used products. CNT usage in electronics, such as biosensing, energy and data storage devices, is discussed. CNT-based field emission devices, which showed outstanding results are also discussed. The current challenges of CNT-based electronics and the future of CNT in electronics applications are mentioned.
Graphical Abstract
“… Fig. 1 Schematic structure of defect-free (a) SWCNT, (b) DWCNT, (c) MWCNT (reprinted from reference 21 , under the terms of the Creative Commons CC BY license). …”
Electronic products are becoming an essential part of our daily life. There is a huge demand to produce small and portable but powerful electronic products. Carbon nanotubes (CNTs) have excellent electrical, mechanical and thermal properties which can be exploited to build next-generation electronics. This paper reviews different types and properties of CNTs and also presents the CNT-based electronics along with their advantage over the conventionally used products. CNT usage in electronics, such as biosensing, energy and data storage devices, is discussed. CNT-based field emission devices, which showed outstanding results are also discussed. The current challenges of CNT-based electronics and the future of CNT in electronics applications are mentioned.
Graphical Abstract
“…In this regard, a number of methods, such as spectrophotometry, chromatography, and fluorimetry, are used for monitoring dyes in water samples [18][19][20]. However, electrochemical techniques are preferred due to the ease of handling and high selectivity and sensitivity [21][22][23][24]. Electrodes are modified by suitable modifiers to impart sensitivity characteristics.…”
Methylene blue is a toxic dye that is extensively used as a colorant in textile industries. Industrial effluent containing methylene blue, when drained into water bodies without proper treatment, poses a serious threat to aquatic and human lives. In order to protect the biocycle, various methods have been established to detect and remove hazardous dyes from aqueous systems. Electrochemical methods are preferred, owing to their characteristic features of simplicity, portability, potential selectivity, cost effectiveness, and rapid responsiveness. Based on these considerations, an electrochemical sensor consisting of amino-group-functionalized, multi-walled carbon nanotubes (NH2-fMWCNTs) immobilized on a glassy carbon electrode (GCE) was developed for the sensitive detection of methylene blue in aqueous solutions. The performance of the designed sensor was analyzed by electrochemical impedance spectroscopy, cyclic voltammetry, and square wave voltammetry. The developed sensing tool demonstrated promising features of sensitivity, selectivity, stability, fast responsiveness, and the ability to work with a very small volume of the analyte, i.e., in microliters, for analysis. Amino groups rich in electrons provide a negative charge to multi-walled carbon nanotubes, which significantly enhances the electrocatalytic activity of NH2-fMWCNTs for cationic dyes such as methylene blue. Using the designed sensing platform, a linear calibration plot with a limit of detection of 0.21 nM was obtained for methylene blue under optimized conditions. The designed sensor was also employed to monitor the extent and kinetics of the degradation of methylene blue. Titania nanoparticles were used for photocatalytic degradation, and the kinetics of degradation was monitored by both UV-Visible spectroscopic and electrochemical methods. The results revealed more than 95% removal of methylene blue in a time span of just 30 min.
“…Functionalized CNT is known as one of the most popular nanocarriers due to its high specific surface area and it can be used for effective drug delivery 115 . In addition, CNT can kill or suppress bacteria 116 . CNT‐based dressings have been shown to increase fibroblast cells migration and proliferation and also have a significant effect on angiogenesis potential l 117,118 …”
Section: Wound Dressingsmentioning
confidence: 99%
“… 115 In addition, CNT can kill or suppress bacteria. 116 CNT‐based dressings have been shown to increase fibroblast cells migration and proliferation and also have a significant effect on angiogenesis potential l. 117 , 118 …”
Wound healing is a complex process in tissue regeneration through which the body responds to the dissipated cells as a result of any kind of severe injury. Diabetic and non-healing wounds are considered an unmet clinical need. Currently, different strategic approaches are widely used in the treatment of acute and chronic wounds which include, but are not limited to, tissue transplantation, cell therapy and wound dressings, and the use of an instrument. A large number of literatures have been published on this topic; however, the most effective clinical treatment remains a challenge. The wound dressing involves the use of a scaffold, usually using biomaterials for the delivery of medication, autologous stem cells, or growth factors from the blood. Antibacterial and anti-inflammatory drugs are also used to stop the infection as well as accelerate wound healing. With an increase in the ageing population leading to diabetes and associated cutaneous wounds, there is a great need to improve the current treatment strategies. This research critically reviews the current advancement in the therapeutic and clinical approaches for wound healing and tissue regeneration. The results of recent clinical trials suggest that the use of modern dressings and skin substitutes is the easiest, most accessible, and most cost-effective way to treat chronic wounds with advances in materials science such as graphene as 3D scaffold and biomolecules hold significant promise. The annual market value for successful wound treatment exceeds over $50 billion US dollars, and this will encourage industries as well as academics to investigate the application of emerging smart materials for modern dressings and skin substitutes for wound therapy.cells therapy, platelet therapy, skin tissue engineering, wound dressing, wound healing
Key Messages• treatment of wound healing is currently considered an unmet clinical need • currently heavily under research are growth factors and cytokines released from platelets and leukocytes that have a significant effect on the cellular functions such as migration, differentiation, and proliferation, so they can regulate the wound healing process
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