Carbon nanotubes functionalized electrospun nanofibers formed 3D electrode enables highly strong ECL of peroxydisulfate and its application in immunoassay

Dai, Hong; Xu, Guifang; Zhang, Shupei; Gong, Lingshan; Li, Xiuhua; Yang, Caiping; Lin, Yanyu; Chen, Jinghua

doi:10.1016/j.bios.2014.05.061

Cited by 44 publications

(16 citation statements)

References 20 publications

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“…On the basis of economic criteria and the need for ultrasensitive assays, Dai et al (2014) [231] developed very recently a novel 3D-biosensing platform based on electrospun carbon nanotubes/poly(methyl methacrylate) nanofibres composite bio-functionalised with α-fetoprotein (α-AFP) antibody, via electrostatic interaction. This platform was used to fabricate label-free electrochemiluminescent (ECL) immunosensor to detect α-AFP.…”

Section: Immunosensors Through Electrospinningmentioning

confidence: 99%

Electrospinning-Based Nanobiosensors

Cesare

Macagnano

2015

Electrospinning for High Performance Sensors

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Biological interactions in biosensors occur through different mechanisms, on the basis of the type of biological receptor elements employed therein that confer the biological specificity to the biosensors themselves (biocatalytic, biocomplexing or bioaffinity biosensors). The use of different transduction systems (amperometric, potentiometric, field-effect transistors, piezometric and conductometric) defines the mode of detection. The interest and relevance of nanomaterials in the fabrication of nanobiosensors lie in their extraordinary properties that make them ideally suited and very promising for sensing applications. The resulting nanobiosensors are capable of sensing analytes in traces with fast, precise and accurate biological identification through miniaturised and easy to use systems. These advanced sensors are also characterised by lower detection limits, higher sensitivity values and high stability, and can further offer multi-detection possibilities. These exceptional features make nanobiosensors as the favourite tools in quality control, food safety, and traceability for their capacity of revealing and warning people against the presence of pathogens, toxins and pollutants, as well as bioterrorism agents. Despite the outstanding properties of these nanobiosensors, however, the efficiency of the biorecognition agent and the number of biorecognition sites available for interacting with target analytes can limit the sensitivity of this kind of sensors. The number of available biorecognition sites is directly related to the surface area of the sensor. Electrospinning technology can significantly increase the sensitivity of biosensors by replacing the typical planar interactive surface of conventional biosensors with a mat of electrospun nonwoven nanofibres, thereby taking advantage of the ultrahigh surface area offered by electrospun nanofibres. Moreover, adjusting the electrospinning process to produce

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Section: Immunosensors Through Electrospinningmentioning

confidence: 99%

Electrospinning-Based Nanobiosensors

Cesare

Macagnano

2015

Electrospinning for High Performance Sensors

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“…An electrochemical impedance spectroscopy biosensor for COX-2 biomarker was fabricated using the porous polyaniline nanofibers [29]. However, as far as we know, the electrospinning technique has been rarely used in ECL biosensors [30][31][32][33][34]. Up to now, The ECL analysis of DA using TiO 2 electrospun nanofibers (TiO 2 ENNFs) has not been reported.…”

Section: Introductionmentioning

confidence: 99%

A Label‐free Electrochemiluminescence Sensing for Detection of Dopamine Based on TiO₂ Electrospun Nanofibers

Sun

wang

et al. 2021

Electroanalysis

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TiO 2 electrospun nanofibers (TiO 2 ENNFs) were synthesized with titanium tetraisopropoxide as precursor by an electrospinning process and characterized by SEM, TEM, XRD, XPS, FTÀ IR, UV and FL. For the excellent properties of film formation, Nafion/TiO 2 ENNFs modified electrode was constructed, which exhibited an excellent electrochemiluminescence (ECL) performance and stability while K 2 S 2 O 8 as co-reactant. In the presence of dopamine (DA), the ECL signal quenched, which was due to that DA easily can be oxidized by holes generated by S 2 O 8 2À in electrode surface, thereby inhibiting the formation of TiO 2 *. Based on this, a new ECL method was proposed for DA detection with a linear range from 0.033 μM to 6.7 μM. The detection limit was 0.017 μM and it was applied in the detection of DA in dopamine hydrochloride injection with satisfactory results.

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“…Since the first detailed studies in the mid-1960s, over 1000 papers, patents, and book chapters have been published on ECL, ranging from the very fundamental to the very applied. Recently, ECL has been used extensively as a powerful analytical tool in many areas such as immunoassay [2][3][4], clinical diagnosis [5,6], and the analysis of food and water [7]. Luminophores can be divided into organic and inorganic luminophores such as luminol, lucigenin, tris(bipyridine)ruthenium(II), and Ru(bpy) 3 2+ , and they have been widely used in immunoassay and DNA analysis because they result in light emission and allow for detection of the emitter at very low concentrations [8,9].…”

Section: Introductionmentioning

confidence: 99%

Electrochemiluminescence Biosensor Based on Thioglycolic Acid-Capped CdSe QDs for Sensing Glucose

Jung

et al. 2016

Journal of Nanomaterials

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In order to detect low level glucose concentration, an electrochemiluminescence (ECL) biosensor based on TGA-capped CdSe quantum dots (QDs) was fabricated by the immobilization of CdSe QDs after modifying the surface of a glassy carbon electrode (GCE) with 4-aminothiophenol diazonium salts by the electrochemical method. For the detection of glucose concentration, glucose oxidase (GOD) was immobilized onto the fabricated CdSe QDs-modified electrode. The fabricated ECL biosensor based on TGA-capped CdSe QDs was characterized using a scanning electron microscope (SEM), UV-vis spectrophotometry, transmission electron microscopy (TEM), a fluorescence spectrometer (PL), and cyclic voltammetry (CV). The fabricated ECL biosensor based on TGA-capped CdSe QDs is suitable for the detection of glucose concentrations in real human blood samples.

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Carbon nanotubes functionalized electrospun nanofibers formed 3D electrode enables highly strong ECL of peroxydisulfate and its application in immunoassay

Cited by 44 publications

References 20 publications

Electrospinning-Based Nanobiosensors

Electrospinning-Based Nanobiosensors

A Label‐free Electrochemiluminescence Sensing for Detection of Dopamine Based on TiO₂ Electrospun Nanofibers

Electrochemiluminescence Biosensor Based on Thioglycolic Acid-Capped CdSe QDs for Sensing Glucose

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Carbon nanotubes functionalized electrospun nanofibers formed 3D electrode enables highly strong ECL of peroxydisulfate and its application in immunoassay

Cited by 44 publications

References 20 publications

Electrospinning-Based Nanobiosensors

Electrospinning-Based Nanobiosensors

A Label‐free Electrochemiluminescence Sensing for Detection of Dopamine Based on TiO2 Electrospun Nanofibers

Electrochemiluminescence Biosensor Based on Thioglycolic Acid-Capped CdSe QDs for Sensing Glucose

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A Label‐free Electrochemiluminescence Sensing for Detection of Dopamine Based on TiO₂ Electrospun Nanofibers