“…There were different methods in the literature for the deoximation of oxime group [5][6][7][8][9][10][11][12][13][14][15][16][17][18][19][20]. We have adopted the deoximation reaction of 8-10 using mild oxidizing agent 2-iodoxybenzoic acid catalyzed by -cyclodextrin in water at room temperature.…”
A new class of thiadiazoles, triazoles and oxadiazoles were prepared from phenacylsulfonylacetic ester by protecting the carbonyl group by oximation. Deoximation was affected by using β‐cyclodextrin in the presence of an oxidizing agent.
“…There were different methods in the literature for the deoximation of oxime group [5][6][7][8][9][10][11][12][13][14][15][16][17][18][19][20]. We have adopted the deoximation reaction of 8-10 using mild oxidizing agent 2-iodoxybenzoic acid catalyzed by -cyclodextrin in water at room temperature.…”
A new class of thiadiazoles, triazoles and oxadiazoles were prepared from phenacylsulfonylacetic ester by protecting the carbonyl group by oximation. Deoximation was affected by using β‐cyclodextrin in the presence of an oxidizing agent.
“…[1][2][3] These compounds are also useful protecting groups in organic syntheses 4 and have found extensive application in the isolation of carbonyl compounds. [5][6] Several methods based on reductive, hydrolytic, and oxidative reactions have been developed for the cleavage of oximes. [7][8][9] Owing to the considerable importance of such compounds there is still scope for newer methods as the existing oxidative methods suffer from disadvantages such as long reaction time, 10 formation of over oxidation products and difficulties in isolation of products.…”
In this work, oximes are converted to their corresponding carbonyl compounds in good yields using N-bromo-N-phenyl-para-toluenesulfonamide, under microwave irradiation. The simple work-up procedure minimizes loss of product.
“…[1][2][3][4][5][6][7][8][9][10][11][12][13] Extensive studies on the deprotection of these derivatives have been carried out using various catalysts.…”
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