Bioactive Carboxylic Compound Classes: Pharmaceuticals and Agrochemicals 2016
DOI: 10.1002/9783527693931.ch10
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Carboxylic-Acid-Based Neuraminidase Inhibitors

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“…In this study, Li-AA-TA-PAM hydrogels were synthesized via free-radical polymerization using a copolymer of acrylamide (AM) and acrylic acid (AA) as the primary framework. The copolymer monomers formed hydrogen bonds between their carboxyl and amide groups, with stronger interactions attributed to the high acidity of carboxylic acid , compared to amide groups alone. Moreover, the absence of secondary electrostatic repulsions further enhanced the strength of hydrogen bonds involving carboxyl groups over those solely between carboxyl groups.…”
Section: Introductionmentioning
confidence: 99%
“…In this study, Li-AA-TA-PAM hydrogels were synthesized via free-radical polymerization using a copolymer of acrylamide (AM) and acrylic acid (AA) as the primary framework. The copolymer monomers formed hydrogen bonds between their carboxyl and amide groups, with stronger interactions attributed to the high acidity of carboxylic acid , compared to amide groups alone. Moreover, the absence of secondary electrostatic repulsions further enhanced the strength of hydrogen bonds involving carboxyl groups over those solely between carboxyl groups.…”
Section: Introductionmentioning
confidence: 99%