Carboxymethyl cellulose as a green and biodegradable catalyst for the solvent-free synthesis of benzimidazoloquinazolinone derivatives

Novel magnetic propylsulfonic acid-anchored isocyanurate-based periodic mesoporous organosilica (Iron oxide@PMO-ICS-PrSO3H) as a highly efficient and reusable nanoreactor for the sustainable synthesis of imidazopyrimidine derivatives

“…Because of the importance of imidazopyrimidine scaffold, different homogeneous or heterogeneous acidic catalytic systems have been investigated to promote multicomponent condensation of 2-aminobenzoimidazole, aromatic aldehydes and C-H acids such as dimedone/malononitrile or relevant synthons. Some of the recent examples of reported catalysts are H 6 P 2 W 18 O 62 .18H 2 O 83 , WO 3 -supported sulfonic acid 84 , O-sulfonated poly(vinylpyrrolidonium) hydrogen sulfate 85 , modified ZnO nanoparticles under ball milling conditions 86 , organo-sulfonic acid tags anchored on magnetic titana coated NiFe 2 O 4 nanoparticles 87 , Fe 3 O 4 @GO 88 , magnetic Irish moss 80 , carboxymethyl cellulose 89 , NH 2 SO 3 H 90 , p-toluenesulfonic acid monohydrate 91,92 , Fe 3 O 4 @clay 93 , L-proline 94 , molecular iodine 95 , polyethylene glycol methacrylate-grafted dicationic imidazolium-based ionic liquid 96 and NaHSO 4 modified phenylene bridged periodic mesoporous organosilica magnetic nanoparticles 55 . In spite of their merits, the existing methodologies have drawbacks such as low to moderate yields, difficulties in the catalyst recovery and product isolation, toxic or expensive catalysts, lengthy reaction times, the use of volatile organic solvents or significant amounts of waste materials production 97 .…”

“…To address limitations and disadvantages associated with these catalytic systems, preparation and catalytic application of magnetic isocyanurate-based propylsulfonic acid periodic mesoporous organosilica (Iron oxide@PMO-ICS-PrSO 3 H), as a novel and highly efficient heterogeneous mesoporous catalyst, would be very desirable. In continuation of our research interest to develop and improve novel and efficient catalysts for different MCRs or organic transformations 34,35,51,52,73,74,89,98,99 , we wish herein to report the application of Iron oxide@PMO-ICS-PrSO 3 H (1), as a novel recyclable catalyst, for the synthesis of imidazopyrimidine derivatives through the Traube-Schwarz multicomponent reaction under solvent-free conditions. To the best of our knowledge, there is no report on the use of Iron oxide@PMO-ICS-PrSO 3 H, as a nanao-architectured heterogeneous and recoverable catalyst, for different organic transformations (Scheme 1).…”

Facile synthesis of triazolo/benzazolo[2,1-b]quinazolinone derivatives catalyzed by a new deep eutectic mixture based on glucose, pregabalin and urea

“…Then these intermediates lead to III or III′ which, by intermolecular cyclization followed by removal of a molecule of water, afford the desired products. 51…”

Bio‐Based Hybrid Catalysts for the Synthesis of Pharmacologically Active Xanthenes

“…In recent decades, following the principles of green chemistry, the synthesis and utilization of biocompatibility, environmentally friendly, and naturally occurring catalysts have become a severe study subject. [1] Dextrin is an inexpensive water-soluble polysaccharide and is generally used as a binding or thickening agent in industrial applications. [2] Dextrins are produced by acid or enzyme-cutting starch.…”