Carcinoid Tumor of the Cecal Appendix

Abstract

Cecal appendix tumors are unusual and have a low frequency of presentation, which is reported between 0.2 and 0.5% of all digestive tract tumors. From the mentioned tumors, the carcinoid ones are the most common neoplasms of the cecal appendix and are characterized in most cases by slow growth and an asymptomatic clinical course. However, in some cases, they can present as a metastatic disease with fatal outcomes. We report the case of a 24-year-old female patient with a typical case of acute appendicitis, in whom an additional diagnosis of a carcinoid tumor is obtained upon receipt of the pathology report. The prognosis of appendicular carcinoid tumors is good, with a five-year survival rate of 95%-100% and a recurrence rate of less than 1%.

Clinico-Pathological Characteristics and Long-Term Outcomes of Incidental Appendiceal Carcinoid Tumors in Children

“…Therefore, proliferation markers, particularly Ki-67 (an indicator of mitotic activity), have become increasingly important in the evaluation of neuroendocrine tumors (NETs) (14). The World Health Organization (WHO) and the European Neuroendocrine Tumor Society (ENETS) have categorized NETs into three groups based on the grade, Ki-67 proliferation index, and mitotic activity.…”