Carcinoid Tumors of the Larynx

Guerrier, Y; Lallemant, J. G.; Charlin, Bernard; Pages, A

doi:10.1159/000275755

Cited by 8 publications

(2 citation statements)

References 5 publications

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“…The literature on NCL is fragmented over numerous case reports and series of small sample size, often with contradicting results, making it difficult to decide on an appropriate treatment strategy. Consequently, physicians facing these tumors often resort to treatment paradigms developed for better known neoplasms (eg, squamous cell carcinoma).…”

Section: Introductionmentioning

confidence: 99%

Clinical recommendations on the treatment of neuroendocrine carcinoma of the larynx: A meta-analysis of 436 reported cases

et al. 2014

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Section: Introductionmentioning

confidence: 99%

Clinical recommendations on the treatment of neuroendocrine carcinoma of the larynx: A meta-analysis of 436 reported cases

et al. 2014

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“…However, based on previous data, carcinoid tumors (typical and atypical) are usually treated by surgery (partial or total laryngectomy) [25][26][27], while neck management can be different. In particular, in patients affected by typical carcinoid, neck dissection is not mandatory due to the low incidence of neck metastasis [14]; on the other hand, in the atypical carcinoid, elective or therapeutic neck dissection is necessary including at least levels IIa and III [14,28]. By contrast, the best option to achieve local control of SCNEC laryngeal tumors continues to be concurrent chemoradiation therapy [29].…”

Section: Neuroendocrine Tumorsmentioning

confidence: 99%

Non-Squamous Cell Carcinoma of the Larynx: A State-of-the-Art Review

Chiesa‐Estomba

Barillari

Mayo‐Yáñez

et al. 2023

JPM

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(1) Background: Non-squamous cell laryngeal carcinoma includes endothelial tumors, such as minor salivary gland tumors, lymphoepithelial tumors, neuroendocrine tumors, soft and hard tissue sarcomas, and malignant melanomas. (2) Methods: A state-of-the-art review using the MEDLINE/PUBMED, Google Scholar, Ovid Medline, Embase, and Scopus electronic databases was performed. (3) Conclusions: In order to optimize overall treatment outcomes, a multidisciplinary, patient-centered approach to the management of non-SCC of the larynx must be adopted universally; a national or international registry on non-SCC laryngeal cancer can be useful to improve understanding about the behavior of this kind of tumor.

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Neuroendocrine tumors of the larynx

Moisa

1991

Head & Neck

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A review of the international literature has revealed 68 paragangliomas, 42 large cell, and 74 small cell tumors of the larynx. Paragangliomas are usually benign, although malignant cases have been reported. Large cell tumors are malignancies associated with a high incidence of early cervical metastasis. Small cell tumors are aggressive cancers characterized by early, diffuse metastatic disease. All three neoplasms demonstrate a propensity for the supraglottic larynx. While surgery remains the treatment of choice for paragangliomas and large cell cancers, small cell cancers are best treated by radiotherapy and chemotherapy. The determinate 5-year survival for patients with paragangliomas, large cell, and small cell cancers is 60%, 34%, and 14%, respectively. While representing distinct clinical entities, these neoplasms demonstrate similar ultrastructural and histochemical features and should be classified as neuroendocrine tumors of the larynx (NETL). A comprehensive analysis of these laryngeal tumors is presented herein. Their clinical behavior and management options are reviewed and a scheme for their nomenclature and classification is proposed.

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Carcinoid Tumors of the Larynx

Abstract: Carcinoid tumors of the larynx are very rare: only 11 cases have been described in the available literature. We report another case, and discuss the nature of the cells of origin and the relationship between these tumors and another rare laryngeal tumor, the oat cell carcinoma.

Cited by 8 publications

References 5 publications

Clinical recommendations on the treatment of neuroendocrine carcinoma of the larynx: A meta-analysis of 436 reported cases

Clinical recommendations on the treatment of neuroendocrine carcinoma of the larynx: A meta-analysis of 436 reported cases

Non-Squamous Cell Carcinoma of the Larynx: A State-of-the-Art Review

Neuroendocrine tumors of the larynx

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