Carcinoma of the cervix: dynamic MR imaging.

Abstract

Dynamic magnetic resonance (MR) imaging was performed to evaluate eight normal uteri and 29 cervical carcinomas. After rapid injection of gadopentetate dimeglumine, dynamic images were obtained every 30 seconds with the spin-echo (SE) technique in the sagittal plane or the fast low-angle shot (FLASH) technique in the axial plane. In the normal uterus, initial slight enhancement of the junction between endometrium and myometrium was followed by enhancement of the uterine myometrium. Cervical carcinoma was readily distinguished from the cervical stroma and myometrium in the early dynamic phase (30-60 seconds). Tumor-cervix contrast in the early dynamic phase was significantly more marked with the dynamic SE technique than with T2-weighted or contrast material-enhanced T1-weighted imaging (P less than .01). For the evaluation of parametrial invasion, the dynamic FLASH study showed better contrast than did T2-weighted images. Among 18 patients who underwent surgery, accurate assessment of the degree of stromal invasion and tumor size was possible with dynamic MR images in 14 patients (78%), T2-weighted images in 11 (61%), and postcontrast T1-weighted images in seven (39%).

Apparent diffusion coefficient in cervical cancer of the uterus: comparison with the normal uterine cervix

“…For the diagnosis of tumor spread, conventional T1-and T2-weighted images provide fairly good information [24][25][26], and dynamic contrast-enhanced images can provide more detailed information regarding tumor spread and vascularity [27][28][29][30][31]. In this study, among nine patients who received radiation therapy or chemoradiation therapy, complete remission was found in all but two of them.…”

Comparison of T2-weighted and contrast-enhanced T1-weighted MR imaging at 1.5 T for assessing the local extent of cervical carcinoma

“…A few reports conclude the usefulness of dynamic MRI when assessing the stromal invasion [24,25]. On the other hand, to our knowledge, no report has emphasized the value of static contrast-enhanced T1-weighted imaging.…”

Role of diffusion-weighted imaging in the diagnosis of gynecological diseases

“…For the diagnosis of tumor spread, conventional T1-and T2-WI provide fairly good information and dynamic contrast-enhanced images can provide details on tumor spread and vascularity ( Fig. 1) [24,[29][30][31][32][33][34]. According to Naganawa et al [12], the mean ADC value of cervical cancer lesions was lower than of normal cervical tissue (1.09 × 10 −3 vs 1.79 × 10 −3 mm 2 /s); it returned to the normal range after chemotherapy and/or radiation therapy.…”