Carcinoma of the Cervix Uteri in Ibadan: Coital Characteristics

Adelusi, B

doi:10.1002/j.1879-3479.1977.tb00633.x

Cited by 15 publications

(7 citation statements)

References 19 publications

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“…The high incidence observed in this study is comparable to that of Ibadan (Nigeria) [15], and other developing nations such as Ghana (Kumasi) [19] and Iran [26]. This is saddening as it is a highly preventable cancer.…”

Section: Discussionsupporting

confidence: 64%

“…This high incidence was also observed in Ibadan and Maiduguri (Nigeria) with 62.7% and 72.6% respectively [12,14,15]. …”

Section: Discussionmentioning

confidence: 59%

“…The incidence differs from one [12–15] place to another with a significant gap between the developing and developed nations. The fact still remains that it is the commonest gynecological cancer in the developing nations [16,17].…”

Section: Discussionmentioning

confidence: 99%

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ecancermedicalscience

Oguntayo

Zayyan²,

Kolawole³

et al.

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Objective:Carcinoma of the cervix is still the most common gynecological malignancy among women in the developing nations. The purpose of this study is to review the pattern of carcinoma of the cervix in Zaria, Northern Nigeria.Method:This is a retrospective study of patients seen at the Gynecologic oncology unit of Ahmadu Bello University Teaching Hospital, Zaria, Nigeria between November 2005 and November 2009.Results:A total of 406 gynecological cancers were identified during the period under review. Carcinoma of the cervix accounted for 65.7 % (267) of histologically confirmed gynecological cancers. Most of the patients were married 265 (99.2 %) and 40% were in the second order of marriage; 57.1% of these women were in a polygamous setting. Two hundred and two (75.6 %) patients fell in the 40Œ69 year age bracket, with a mean age of 44.5 years. The disease appears to be associated with high parity (range of 0Œ14); grand multiparous patients constituted 145 (68.3%) of the cases. Abnormal vaginal bleeding (219 patients: 82 %), offensive vaginal discharge (120 patients: 44.9%) and post-coital bleeding (56 patients: 20.9%) were the most common symptoms. About 78% of the patients had advanced disease, stage III disease being the commonest stage accounting for 159 (59.5 %). Fifty-six (21%) of these patients presented with vesico-vaginal fistula.Conclusion:This study demonstrates that in the northern part of Nigeria 65.7% of all gynecological cancers are carcinoma of the cervix. This high percentage appears to be connected with some detrimental sociocultural practices, such as early onset of sexual activity, which should be addressed. More emphasis should be given to screening programs for women in under-developed countries.

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Section: Discussionsupporting

confidence: 64%

“…This high incidence was also observed in Ibadan and Maiduguri (Nigeria) with 62.7% and 72.6% respectively [12,14,15]. …”

Section: Discussionmentioning

confidence: 59%

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ecancermedicalscience

Oguntayo

Zayyan²,

Kolawole³

et al.

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“…Many patients abstained from intercourse because of a fear of recurrence, especially in those who had therapeutic doses of radiotherapy and therefore had a good prognosis. It is known that early onset and high frequency of coitus are causative factors for cancer of the cervix (Stern and Dixon, 1961;Rotkin and King, 1962;Boyd and Doll, 1964;Christopherson and Parker, 1965;Adelusi, 1977), but there is no evidence of a relationship between coitus after radiotherapy and recurrence of the malignancy, and patients should be made to realise this, particularly as they may fear that their illness was due to past misdeeds which must not be repeated.…”

Section: Discussionmentioning

confidence: 99%

“…THE literature contains few reports on the effects of treatment of carcinoma of the cervix on the sexual life of the patient (Huffman, 1950;Vasicka et al, 1958;Decker and Schwartzman, 1962;Abitbol and Davenport, 1974), despite the fact that first coitus at an early age and multiple sexual partners have been implicated in the aetiology of the disease (Adelusi, 1977). This scientific lack of interest may be due to the widespread myth that intercourse is unusual for women beyond the middle age.…”

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confidence: 99%

Coital Function After Radiotherapy for Carcinoma of the Cervix Uteri

Adelusi

1980

BJOG

Self Cite

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The interference of treatment with the sexual life of the patient is an important but relatively neglected aspect of the study of carcinoma of the cervix uteri. In a study of the coital function of patients who had radiotherapy for Stages I to I11 (FIGO Classification) carcinoma of the cervix in the University College Hospital (UCH), Ibadan, Nigeria, dyspareunia and the fear of recurrence of the malignancy accounted for a marked reduction in the frequency of intercourse after treatment of their disease. A significant finding was the disruption in marital relationships directly attributable to the illness. Steps to minimise these problems are discussed.

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Human papillomavirus (HPV) infection, hiv infection and cervical cancer in Tanzania, East Africa

Meulen

Eberhardt

Luande

et al. 1992

Intl Journal of Cancer

118

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The presence of HPV-DNA was determined in tumor biopsies of cervical-cancer patients and in cervical swabs of non-cancer patients from Tanzania, East Africa, by Southern blot hybridization and/or PCR. HPV types 16 and 18 were detected in 38% and 32%, respectively, of 50 cervical-carcinoma biopsies. A consensus primer PCR capable of detecting a broad spectrum of HPV types revealed the presence of HPV-DNA in 59% of 359 cervical swabs of non-cancer patients. Type-specific PCR showed that types 16 and 18 accounted for 13.2% and 17.5%, respectively, of all HPV infections. Therefore we concluded that HPV 18 is more prevalent in Tanzania than in any other geographical location so far reported. The strongest risk factors for the presence of any HPV-DNA in the 359 female non-cancer patients were young age and HIV infection. The epidemiology of HPV types 16 and 18 was found to differ from that of other HPV types, being associated in univariate analysis with trichomonas vaginalis infection, martial status (single/divorced), age at first intercourse, and young age at menarche. However, young age at menarche accounted for most of the effects of all other, variables in multivariate analysis. Of the non-cancer patients, 12.8% had antibodies against HIV I (no patient being severely symptomatic), and HIV infection was highly correlated with the presence of HPV-DNA, especially types 16 and 18. While HPV-DNA of any type was detectable 1.4-fold more often in HIV-positive patients than in HIV-negative patients, evidence of an infection with HPV types 16 or 18 was found 2.2-fold more often in the HIV-positive patients. The HIV-positive women did not show an increased rate of cervical cytological abnormalities as assessed by PAP staining of a single cervical smear, the overall rate of abnormalities being 2.8%. Furthermore, the age-adjusted prevalence of HIV antibodies was found to be considerably lower in 270 cervical-carcinoma patients (3% HIV-positive) in comparison with non-cancer patients. Thus there was no association observable between the prevalence of HIV infections and the frequency of cervical cytological abnormalities or cervical cancer in the setting of this cross-sectional study.

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Carcinoma of the Cervix Uteri in Ibadan: Coital Characteristics

Cited by 15 publications

References 19 publications

ecancermedicalscience

ecancermedicalscience

Coital Function After Radiotherapy for Carcinoma of the Cervix Uteri

Human papillomavirus (HPV) infection, hiv infection and cervical cancer in Tanzania, East Africa

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